Which is more serious, anal canal cancer or rectal cancer?

Written by Sun Wei
Surgical Oncology
Updated on April 21, 2025
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Rectal cancer and anal canal cancer both belong to the category of malignant tumors of the digestive system, with anal canal cancer generally considered a type of rectal cancer, primarily occurring at the anal canal close to the anus. Comparatively, anal canal cancer is somewhat more serious than rectal cancer. Clinically, the closer the tumor is to the anus, the potentially higher the malignancy, meaning more severe. However, subsequent treatment outcomes also need to be considered. Both anal canal cancer and rectal cancer can be considered for curative surgery. If the cancer is very close to the anus and an anus-preserving surgery is not feasible, further colostomy surgery may be required.

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Rectal cancer is primarily a malignant tumor, and there are individual differences in treatment, even differing biological behaviors. Some people discover it early, while others find it later, sometimes even with multiple metastases. If it is diagnosed in a later stage, naturally, the patient's survival period is shorter. Surgical treatment of rectal cancer is one aspect, and subsequent measures to possibly extend the patient's survival include radiotherapy, chemotherapy, targeted therapy, immunotherapy, etc.

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Can a colonoscopy detect colon and rectal cancer?

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