Which is more serious, anal canal cancer or rectal cancer?

Written by Sun Wei
Surgical Oncology
Updated on April 21, 2025
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Rectal cancer and anal canal cancer both belong to the category of malignant tumors of the digestive system, with anal canal cancer generally considered a type of rectal cancer, primarily occurring at the anal canal close to the anus. Comparatively, anal canal cancer is somewhat more serious than rectal cancer. Clinically, the closer the tumor is to the anus, the potentially higher the malignancy, meaning more severe. However, subsequent treatment outcomes also need to be considered. Both anal canal cancer and rectal cancer can be considered for curative surgery. If the cancer is very close to the anus and an anus-preserving surgery is not feasible, further colostomy surgery may be required.

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Hemorrhoids bleeding and rectal cancer bleeding

Hemorrhoids or colorectal cancer can both cause local bleeding in the anal area, but there are clear differences between hemorrhoidal bleeding and colorectal cancer bleeding in clinical practice. Hemorrhoidal bleeding is mostly bright red and does not mix with the stool; it is separate bleeding. It may manifest as blood on the finger, or as dripping or spurting blood. Colorectal cancer bleeding, on the other hand, is generally dark red and mixes with the stool, sometimes accompanied by pus and blood. Bleeding from colorectal cancer mainly occurs in the late stages of the disease, usually caused by local mucosal ulceration or tumor rupture. During hemorrhoidal bleeding, an anal scope examination can reveal clear bleeding points above and below the dentate line, while bleeding from colorectal cancer requires examination with an electronic colonoscope to observe the local tumor area, which may show mucosal damage or ulcers.

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Written by Gong Chun
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What are the symptoms and early signs of rectal cancer?

In the early stages of rectal cancer, there are no obvious symptoms. Only when the condition progresses to a certain extent do some clinical symptoms appear. The first is a change in bowel habits or the nature of the stool. The second possible symptom is abdominal pain. The third possible outcome is intestinal obstruction. The fourth symptom occurs when the tumor develops to a certain extent, and lumps can be felt in the abdomen. The fifth point includes possible symptoms of systemic poisoning such as anemia, weight loss, fever, and weakness. The sixth point is that in the advanced stages of rectal cancer, some metastatic lesions may appear, such as extensive pelvic metastasis and infiltration, leading to pain in the sacral area and sciatic neuralgia; if areas like the vaginal, rectal mucosa, or bladder mucosa are involved, there may be vaginal bleeding or blood in the urine, resulting in conditions like rectovaginal or rectovesical fistulas.

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What are the symptoms of rectal cancer?

Symptoms of rectal cancer include changes in bowel habits, such as a feeling of heaviness around the anus, a constant need to defecate, or diarrhea. Some patients may experience constipation, or alternating episodes of diarrhea and constipation. Another common symptom is a change in the shape of the stool, with the stool becoming narrower. Additionally, abdominal pain and rectal bleeding are also common symptoms. Some patients with rectal cancer may exhibit clinical signs of intestinal obstruction, which includes constipation, inability to pass stool or gas, which means no flatulence. This is accompanied by nausea and vomiting. Other common symptoms include significant abdominal pain and bloating.

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Is rectal cancer hereditary?

This answer is also possible, as one of the causes of any cancer includes the possibility of genetics. However, this possibility is generally small and not everyone is likely to have it. It also depends on the incidence of disease within the entire family. If one is in a high-risk category due to certain genetic factors, then it is crucial to have regular and thorough follow-up checks. Some people might even try treatments specifically targeting genetically inherited colorectal cancer.

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Written by Wang Hui Jie
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Can a colonoscopy detect rectal cancer?

Colonoscopy can detect colon and rectal cancer. It is the most important and primary method for examining colonic mucosal lesions. The large intestine includes the cecum, colon, and rectum. Colonoscopy allows direct visual inspection of lesions, including the size and color of the lesions, and whether there are ulcers and erosion, the nature of any attachments, etc. It also allows for direct biopsy. Firstly, it can assess the texture of the lesion, such as whether it is soft, hard, or brittle. Moreover, the biopsied sample can be analyzed histologically to determine the benign or malignant nature, depth of infiltration, etc. Different pathological characteristics have different prognoses and treatment methods, suitable for early cancers treatable under endoscopy, or those that can be removed during the process of the colonoscopy.