Is rectal cancer hereditary?

Written by Zhang Peng
General Surgery
Updated on December 29, 2024
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This answer is also possible, as one of the causes of any cancer includes the possibility of genetics. However, this possibility is generally small and not everyone is likely to have it. It also depends on the incidence of disease within the entire family. If one is in a high-risk category due to certain genetic factors, then it is crucial to have regular and thorough follow-up checks. Some people might even try treatments specifically targeting genetically inherited colorectal cancer.

Other Voices

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Written by Gong Chun
Oncology
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Can rectal cancer be detected by ultrasound B?

Can rectal ultrasound detect it? When we perform an abdominal ultrasound for the digestive system, we might see a potential mass in the abdomen, but its specific nature cannot be clearly identified. Therefore, the definitive diagnosis of rectal cancer still relies on biopsy and pathological examination. Thus, it is recommended to go to the hospital and consult a professional oncologist for tests, such as undergoing an endoscopic biopsy or having a surgical procedure to remove and then analyze the pathology to confirm whether it is rectal cancer or not.

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Written by Sun Wei
Surgical Oncology
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Is anal canal cancer considered a type of rectal cancer?

Anal canal cancer can also be considered a type of rectal cancer, specifically the type located near the anus, referred to as anal canal cancer. Generally, anal canal cancer may have a higher malignancy level, and its initial main symptoms include rectal bleeding and changes in stool characteristics, such as narrower stools. There may also be a sensation of heaviness and pain in the anal area. Diagnosis is typically confirmed through a digital rectal examination and a biopsy. If necessary, an anoscopy and other common examinations can be conducted to check for lesions in other parts of the intestine. Generally, the prognosis for anal canal cancer is not as favorable as for other types of rectal or colon cancer.

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Written by Si Li Li
Gastroenterology
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Is rectal bleeding an indication of rectal cancer?

Rectal bleeding is not necessarily colorectal cancer; there are several reasons for rectal bleeding: First, caused by constipation, which leads to difficulty during bowel movements and tearing of the anal mucosa, resulting in bleeding. Second, ulcerative colitis, which commonly presents symptoms such as abdominal pain, diarrhea, and blood and mucus in the stool. Third, rectal or colon cancer, where the main symptoms also include abdominal pain, changes in stool characteristics, and rectal bleeding. Fourth, ischemic bowel disease, generally seen in older patients with some cardiovascular and ischemic diseases, where symptoms mainly include significant abdominal pain and rectal bleeding. Therefore, not all cases of rectal bleeding are due to rectal cancer; there are many causes, and it is essential to diagnose clearly before treatment.

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Written by Liu Liang
Oncology
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Rectal cancer stage III

Rectal cancer staging is based on the TNM system. "T" refers to the primary tumor, and its stage depends on which layer of the bowel wall the tumor has invaded. "N" is based on whether there are lymph node metastases and the number of lymph nodes involved. "M" indicates whether there are metastases to distant organs. Staging is determined according to the TNM situation, where Stage I is the earliest and Stage IV is the latest. Stage III indicates lymph node metastasis without distant organ metastases, such as to the liver or lungs. In such cases, irrespective of whether T is T1 to T4, if there is lymph node involvement without distant organ metastasis, it is staged as Stage III.

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Written by Liu Liang
Oncology
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Does stage II rectal cancer require chemotherapy?

Whether a stage II colorectal cancer patient needs adjuvant chemotherapy after surgery depends on the specific circumstances. For example, stage IIA patients are classified as T3, N0, M0. The necessity of adjuvant chemotherapy for these patients should be determined based on the pathological report. If the report indicates the presence of vascular invasion, neural invasion, poor differentiation, or if microsatellite stability testing shows poor prognostic factors, then such patients should undergo postoperative adjuvant chemotherapy. If none of these conditions are present in a stage IIA patient, then postoperative adjuvant chemotherapy may not be necessary. Generally, stage IIB patients, whose tumors have penetrated the full thickness of the intestinal wall, are recommended to undergo postoperative adjuvant chemotherapy. Therefore, the specific conditions of the patient need to be considered.