Stage IV rectal cancer

Written by Liu Liang
Oncology
Updated on September 11, 2024
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In the staging of rectal cancer, we generally use the TNM staging system clinically. "T" refers to the primary tumor, "N" indicates whether there is lymph node metastasis, and staging is based on the status of the lymph nodes. "M" indicates whether there is distant metastasis. Stage IV refers to any stage of "T" and any stage of "N", as long as there is distant metastasis, such as rectal cancer metastasizing to the liver, lungs, or bones. When these distant organ metastases occur, the staging is M1, any "T", any "N", M1. This scenario is stage IV, indicating the presence of distant organ metastasis and represents advanced stage rectal cancer patients.

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Early symptoms of rectal cancer

The early symptoms of rectal cancer generally include five main signs: The first early symptom is bloody stool, which is the earliest and most common symptom of rectal cancer. The second symptom is mucous bloody stool. Large cauliflower-like tumor masses generally secrete a large amount of mucus, which can cause mucous bloody stool. The third is a change in bowel habits. What does a change in bowel habits mean? It means that sometimes there can be diarrhea, sometimes constipation, or an alternation of constipation and diarrhea, indicating a change in bowel habits. There can even be changes in the shape of the stool, which is the third symptom. The fourth symptom is a feeling of heaviness or fullness in the perineum or anus. The fifth symptom can cause abdominal pain. It can cause pain in the lower abdomen, a sensation of a foreign body in the intestine, and even bloating. For instance, constipation can lead to difficulty in passing stool, which in turn can cause bloating and abdominal pain. These are primarily the five early symptoms.

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Can the anus be preserved if the rectal cancer is 3 cm away from the anus?

When rectal cancer is 3cm from the anus, it generally isn't possible to preserve the anus. Currently, the commonly used surgical methods for rectal cancer are the Dixon and Miles techniques. Generally, the threshold is 5cm from the anus; when the tumor is within 5cm of the anus, it often necessitates a Miles procedure, which does not preserve the anus. When the tumor is more than 5cm from the anus, an anus-preserving Dixon procedure can be performed. However, in considering the radical resection of rectal cancer, preserving the anus should not be the primary choice; instead, the main goal should be curative.

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What are the differences between colon cancer and rectal cancer?

The fundamental difference between colon cancer and rectal cancer lies in their locations of occurrence. Both are collectively referred to as colorectal cancer, which is one of the more prevalent malignancies of the digestive system in China. Colon cancer originates from the mucosa of the colon, while rectal cancer originates from the mucosa of the rectum, with different points of origin. In terms of treatment, there are significant differences between colon and rectal cancer. In surgical treatment, both cancers typically require surgery as the first choice. However, patients with colon cancer can preserve their anus, whereas some patients with low rectal cancer might face situations where anus preservation is not possible. In internal medicine, the chemotherapy drugs used for colon and rectal cancer are quite similar. In terms of radiation therapy, there are notable differences; radiation treatment is generally not included for colon cancer but is an important treatment method for rectal cancer.

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What are the symptoms of rectal cancer?

Symptoms of rectal cancer include changes in bowel habits, such as a feeling of heaviness around the anus, a constant need to defecate, or diarrhea. Some patients may experience constipation, or alternating episodes of diarrhea and constipation. Another common symptom is a change in the shape of the stool, with the stool becoming narrower. Additionally, abdominal pain and rectal bleeding are also common symptoms. Some patients with rectal cancer may exhibit clinical signs of intestinal obstruction, which includes constipation, inability to pass stool or gas, which means no flatulence. This is accompanied by nausea and vomiting. Other common symptoms include significant abdominal pain and bloating.

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Can a colonoscopy detect colon and rectal cancer?

Colonoscopy can detect colon and rectal cancers. By conducting a colonoscopy, it can be determined whether a space-occupying lesion is in the colon or the rectum. In the workplace, it can also confirm the distance from the anus in centimeters, to guide the next steps of surgical treatment. If a colon or rectal tumor is found during colonoscopy, a pathological biopsy may be needed. Combined with the pathological biopsy, a diagnosis can be made whether the patient has colon cancer or rectal cancer. At the same time, colonoscopy can also detect other diseases, such as colon polyps, ulcerative colitis, Crohn's disease of the colon, and so on.