Breast distension pain generally does not require the administration of magnesium sulfate, as magnesium sulfate is typically used for cellulitis or inflammation and swelling and needs to be applied externally. Breast distension pain is usually related to breast hyperplasia, which is associated with elevated levels of estrogen in the body. Therefore, it is often treated with traditional Chinese medicine. Techniques such as soothing the liver and regulating the Qi, as well as coordinating the thoroughfare and conception vessels, can relieve pain. Endocrine treatments are also available, though ideally not used unless the pain is very significant during the premenopausal period, in which case it can be taken before the onset of menstruation. Vitamin therapy, including vitamins B, C, and E, can also be used; these improve liver function, regulate basal metabolism, and enhance the functioning of the autonomic nervous system, serving as adjunctive treatments for this condition.