Infant eczema is a common skin condition in babies and toddlers. Generally, we do not recommend the use of calamine lotion for eczema, as although it has an itch-relieving effect when applied locally, it can make the skin even drier. Therefore, if the skin is itchy, temporarily using calamine lotion is possible, but it is not recommended for long-term use in treating eczema. The treatment of eczema consists of 60%-70% moisturizing and 30%-40% may involve the use of mild corticosteroid creams under the guidance of a doctor. Overall, moisturizing is the main treatment for eczema, while hormone therapy can be a supportive treatment. Calamine lotion can be temporarily used to relieve itching, but it is not recommended as a standard treatment method for eczema. Additionally, for infants who are on formula, it is important to use hydrolyzed protein formula, and if breastfeeding, the mother’s diet needs to be carefully managed.