The precocious puberty stimulation test is used to check for what?

Written by Dong Xian Yan
Pediatrics
Updated on September 12, 2024
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The precocious puberty stimulation test, also known as the luteinizing hormone-releasing hormone stimulation test. The method of examination involves administering an intravenous injection of gonadotropin-releasing hormone, followed by taking blood samples before the injection, and at 30, 60, 90, and 120 minutes after the injection. Serum levels of luteinizing hormone and follicle-stimulating hormone are measured to assess their peak values. This can diagnose whether the gonadal axis has been activated and is a reliable method for diagnosing precocious puberty.

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Written by Huang Kun Mei
Pediatrics
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What are the adverse consequences of precocious puberty?

The adverse consequences of precocious puberty are numerous. The most significant impact is on the child's growth, including their psychological health. Precocious puberty particularly affects the height of both boys and girls. For example, girls may experience earlier menstruation and breast development, while boys may experience early voice changes or premature enlargement of the testicles. In such cases, it is crucial first to check the child's bone age to see if it is advanced. If there is advancement, it is essential to medicate the child promptly.

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Written by Quan Xiang Mei
Pediatrics
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Premature breast pain has now stopped hurting, does that mean it's healed?

When girls develop breasts before the age of eight, they may experience pain at the breast bud nodules. Pain does not necessarily mean recovery; it is possible that as the breast bud enlarges, the pain will naturally disappear. Whether treatment is needed once precocious puberty occurs and whether it has reached a level of cure mainly depends on the assessment through pediatric bone age, gonadal ultrasound examinations, or a combination of brain pituitary MRI and blood hormone levels to analyze the severity of the condition. For mild cases, with appropriate medication, diet, and exercise guidance, children can reach a basic level of clinical cure. Severe cases require the control of the child's sexual development through the injection of gonadal hormones or hormone-releasing analogues. Psychological impacts due to early sexual development may also necessitate behavioral and psychological interventions.

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Written by Dong Xian Yan
Pediatrics
37sec home-news-image

The precocious puberty stimulation test is used to check for what?

The precocious puberty stimulation test, also known as the luteinizing hormone-releasing hormone stimulation test. The method of examination involves administering an intravenous injection of gonadotropin-releasing hormone, followed by taking blood samples before the injection, and at 30, 60, 90, and 120 minutes after the injection. Serum levels of luteinizing hormone and follicle-stimulating hormone are measured to assess their peak values. This can diagnose whether the gonadal axis has been activated and is a reliable method for diagnosing precocious puberty.

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home-news-image
Written by Dong Xian Yan
Pediatrics
40sec home-news-image

Does precocious puberty require growth hormone treatment?

For children with precocious puberty, a small number require combined treatment with growth hormones. For instance, if a child's height growth rate is less than 4cm, it is necessary to add growth hormones to promote growth and development. The second scenario involves using a bone age test; if the height is less than 151cm, growth hormones can also be used in combination for treatment. In the third scenario, if the child's bone age at the time of consultation has already exceeded 11.5 years, has significantly increased, or even if menstruation has started and their height has been clearly affected, it is generally advised to use growth hormones in combination with treatment.

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Written by Yan Xin Liang
Pediatrics
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What should I do if I find out my child is maturing early?

Interventional treatment for precocious puberty varies according to different causes. In principle, once diagnosed with central precocious puberty, aggressive pharmacological treatment is recommended, using inhibitory hormones to suppress development to pre-pubertal levels and inhibit further development of the ovaries and uterus. For peripheral precocious puberty or pseudoprecocious puberty, the cause must be removed. Clinically, if a child accidentally ingests their mother's contraceptive pills causing transient vaginal bleeding, it is essential to carefully inquire about the medical history, thoroughly understand the cause, and determine the treatment method. Also, ask if there has been any special dietary intake recently, including foods or drinks high in estrogen, and if so, remove the cause for treatment.