Can cirrhosis caused by hepatitis B virus be cured?

Written by Ye Xi Yong
Infectious Diseases
Updated on September 23, 2024
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Hepatitis B virus-induced cirrhosis was previously considered incurable, though its progression could be slowed. However, recent observations and studies have shown that a small fraction of patients with early-stage hepatitis B virus-induced cirrhosis can be cured. However, the proportion of these patients is extremely low. To draw an analogy, cirrhosis is like our houses. If the cement, steel bars, and brick structure are damaged, then the house is difficult to repair. Cirrhosis is akin to the structural damage of the house, making it hard to recover.

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Written by Wang Ji Zhong
Internal Medicine
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Symptoms of alcoholic liver cirrhosis

Long-term alcohol consumption can lead to alcoholic liver disease, with alcoholic liver cirrhosis being one of its main manifestations. Initially, it presents with reduced liver function, symptoms such as loss of appetite, abdominal pain, bloating, vomiting, aversion to oily foods, diarrhea, and nausea, which are indicative of hepatitis. Additionally, there may be darkening of the skin, menstrual irregularities, and even signs like liver palms and spider angiomas due to metabolic disorders. Furthermore, disruptions in carbohydrate metabolism can lead to nutritional excess, increasing lipid levels in the body and leading to fatty liver and hyperlipidemia. There can also be abnormal protein synthesis, resulting in ascites, pleural effusion, and other symptoms of liver dysfunction. Additionally, abnormalities in vitamin metabolism can cause rough skin and edema. Coagulation factors are often abnormal as well, leading to symptoms such as bleeding gums and nosebleeds. Therefore, it is crucial to seek medical attention promptly in these situations to restore normal health.

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Written by Si Li Li
Gastroenterology
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What are the gastrointestinal symptoms of cirrhosis?

In the early stages of cirrhosis, many patients do not exhibit any symptoms, but some may experience fatigue, nausea, vomiting, poor appetite, and indigestion. Some patients might also suffer from portal hypertensive gastropathy due to cirrhosis, leading to symptoms such as pain and bloating in the upper abdomen, acid reflux, and belching. If the disease progresses to the decompensated stage of cirrhosis, portal hypertension can cause varices in the esophagus and stomach, which may lead to severe upper gastrointestinal bleeding if hard food is consumed. Symptoms can include vomiting dark red blood or fresh blood, dizziness, fatigue, and cold sweats. In such cases, it is advised to seek immediate medical attention for emergency treatment.

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Written by Wu Hai Wu
Gastroenterology
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Is the surface of the liver smooth in the early stages of cirrhosis?

In the early stages of cirrhosis, it is not necessarily the case that the liver surface is very smooth; in patients with early cirrhosis, the liver surface can be uneven. Patients in the early stages of cirrhosis also need serious attention. They should undergo regular follow-up examinations, and it is important to identify the cause of the early cirrhosis. Based on different causes, appropriate treatment measures should be taken. For example, if the early cirrhosis is caused by chronic hepatitis B virus, antiviral treatment should be initiated as soon as possible. If it is due to alcohol, leading to early alcoholic cirrhosis, then it is crucial to quit drinking actively, and liver-protective treatments are also needed.

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Written by Wu Hai Wu
Gastroenterology
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What is the difference between the symptoms of cholecystitis and the symptoms of cirrhosis?

The symptoms of cholecystitis differ significantly from those of cirrhosis. The symptoms of cholecystitis mainly manifest as pain in the upper right abdomen, along with chills and fever, while the symptoms of cirrhosis primarily include fatigue, poor appetite, and may also present with jaundice, abdominal distension, and swelling of the lower limbs. To determine whether a patient has cholecystitis or cirrhosis, it is recommended to visit the gastroenterology department of a standard hospital as soon as possible for a comprehensive examination. This should include abdominal imaging, liver function tests, complete blood count, among others, to further clarify the diagnosis and adopt corresponding treatment measures.

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Written by Wu Hai Wu
Gastroenterology
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Why does cirrhosis cause increasing weight loss and what can be done about it?

The reason why patients with cirrhosis are becoming thinner might be due to the decreased protein synthesis function of the liver after cirrhosis, leading to progressively lesser protein in the body, which results in the patient becoming thinner. It could also be because cirrhosis leads to poor digestion and absorption in patients, thereby reducing their absorption capacity and causing them to lose weight. Under these circumstances, some medications can be used for treatment, such as the infusion of albumin to supplement plasma proteins in the body. It is also important to actively treat the underlying cause of cirrhosis. For example, in the case of alcoholic cirrhosis, active efforts to abstain from alcohol and rehabilitative treatment are necessary. If the cirrhosis is caused by chronic hepatitis B virus infection, antiviral treatment should be administered.