The causes of infertility due to endometriosis

Written by Yue Hua
Obstetrics and Gynecology
Updated on April 06, 2025
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The main reason that endometriosis leads to infertility is that the condition alters the anatomical structure of the pelvic area. It is often found that there are extensive adhesions around the ovaries and fallopian tubes, which can lead to blockage or twisting of the fallopian tubes. This can cause abnormal movement of the fallopian tubes, impacting the transport of the fertilized egg. Additionally, in patients with endometriosis, the pelvic environment is also found to be poor, and some women may experience abnormalities in ovarian function, mainly manifesting as ovulatory disorders. These are all reasons that lead to infertility.

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Written by Zhao Min Ying
Reproductive Medicine
1min 43sec home-news-image

How does infertility arise?

Couples who live together and have normal sexual relations without any contraceptive measures for over a year are diagnosed with female infertility in the case of the woman, and male infertility in the case of the man. Infertility is related to many factors. For men, the main factors are abnormalities in the semen, which include low sperm count, weak sperm motility or even a complete absence of sperm, as well as sexual dysfunction, where various factors prevent the completion of normal sexual activities. For women, the main factors include, first, ovulatory disorders, which are primarily abnormalities in menstruation, although some may have normal menstruation but still experience ovulatory disorders. Second, factors related to the fallopian tubes; these can include previous conditions like pelvic inflammatory disease, appendicitis, etc., or infections caused during procedures involving the uterine cavity leading to blockages in the fallopian tubes, which can be diagnosed via hysterosalpingography. Third, conditions such as endometriosis and adenomyosis, which can also affect the chances of pregnancy. Fourth, factors related to the uterus, such as uterine fibroids, polyps, and malformations, which can create barriers to pregnancy. Lastly, some immunological factors, including antisperm antibodies or other antibody factors, etc.

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Written by Kang Jian Hua
Reproductive Center
59sec home-news-image

What should infertile women check for?

The examination of infertile women mainly includes the following aspects. First is the physical examination, which covers a general examination and an examination of the internal and external genitalia. Through the physical examination, it can be determined whether the female sexual characteristics are normal and whether there are any abnormalities in the development of the external genitalia. The second type of examination is auxiliary examination, the most common of which are blood tests and ultrasound exams. Blood tests can provide information on whether there is any infection, the type of blood, and the endocrine situation. They can also examine chromosomal conditions. Through ultrasound, it is possible to find out if there are any abnormalities in the uterine adnexa. Additionally, there are some special tests, including ovarian function tests, fallopian tube patency tests, hysteroscopy, laparoscopy, and post-coital tests, among others.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
1min 11sec home-news-image

What should I do if I have irregular menstruation and infertility?

If menstrual irregularities lead to infertility, the first step is to go to the hospital for an endocrine test. Menstrual irregularities generally indicate a dysfunction in ovarian function. At this time, you can go to the hospital for a blood test, which should be done on the second to fifth day of the menstrual period. It is important to fast before the blood test. After the blood test, treatment should be based on the results. Generally, patients with menstrual irregularities experience ovulation disorders or ovarian secretion dysfunction, causing abnormal hormone levels in the body, which are not conducive to egg implantation and development. Therefore, if menstrual irregularities lead to infertility, it is essential to undergo relevant medical examinations at the hospital and then treat based on the findings. Moreover, if you have been trying to conceive for over a year without success, be sure to undergo other infertility tests.

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Written by Gan Hai Ying
Obstetrics and Gynecology
1min 3sec home-news-image

Why does premature ovarian failure cause infertility?

The primary reason that premature ovarian failure leads to infertility is due to the decline in ovarian function it causes. Reduced ovarian function results in insufficient secretion of estrogen levels within the body. Consequently, the follicles on the ovaries do not develop and mature, and without mature egg cells, the sperm and egg cannot meet, which leads to infertility. Additionally, women with premature ovarian failure experience low hormone levels that prevent changes in the uterine lining, making it unsuitable for a fertilized egg to implant in the uterine cavity, which also causes infertility. Premature ovarian failure in women often leads to infertility. Therefore, it is difficult for women with this condition to conceive. If childbearing is desired, after treatment to regulate menstruation, it may be necessary to use assisted reproductive technologies such as in vitro fertilization to achieve pregnancy.

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Written by Kang Jian Hua
Reproductive Center
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What is infertility?

Infertility refers to the condition where, despite a couple having regular sexual intercourse without contraception for more than a year, the woman does not become pregnant, at which point infertility is diagnosed. Infertility includes primary infertility and secondary infertility. Primary infertility refers to those who have never been pregnant before; secondary infertility refers to individuals who have previously given birth or been pregnant but later, despite trying to conceive for over a year without contraception and having regular sexual intercourse, are unable to become pregnant.