Enlarged glands can lead to sleep apnea, snoring, decreased hearing, and secondary sinus infections. If the enlargement is simple without these symptoms, it does not affect vaccination. However, if the enlargement leads to acute sinus infection, manifested by chills, fever, a large amount of thick nasal discharge, or pus-like discharge, these are symptoms of an acute infection, and vaccination should not be administered. Appropriate treatment should be given first, and after the condition is controlled, vaccination can then proceed. Simple adenoid hypertrophy does not impact vaccination.