Neonatal jaundice is one of the common symptoms in the neonatal period. It can be a physiological manifestation in the normal development process of newborns, but it can also be an external symptom of certain diseases. Generally, the duration of normal physiological jaundice should not exceed two weeks for full-term infants and four weeks for premature infants. If the jaundice lasts too long, recurs, or is severe, pathological jaundice should be considered. Pathological jaundice might be a manifestation of certain diseases, with bilirubin levels being one of the indicators. If it is accompanied by other discomforts, such as significant vomiting, abdominal distension or diarrhea, drowsiness, refusal to feed, or fever, this indicates a more serious condition. If the jaundice does not subside, it is recommended to seek prompt medical attention at a hospital. If there is a clear pathological cause, intervention and possibly inpatient treatment are required.