neonatal jaundice subsidence time

Written by Li Jiao Yan
Neonatology
Updated on September 01, 2024
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Neonatal jaundice is a common phenomenon and a unique condition in newborns. If it is normal physiological jaundice, it generally subsides within two weeks for full-term infants born after 37 weeks. This means that after two weeks, the jaundice is essentially gone; the skin and eyes are no longer yellow, and bilirubin levels are typically below 6-7, which is considered normal. For premature infants, the jaundice generally clears within four weeks. If the jaundice persists longer, there might be some pathological factors involved, and it is advisable to visit a hospital for a thorough evaluation by a doctor to determine if any special treatment is needed.

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Written by Shi Ji Peng
Pediatrics
44sec home-news-image

Reasons for slow resolution of neonatal jaundice

Newborns may experience physiological jaundice after birth, but due to various reasons, the jaundice may fade slower. Common causes include physiological dehydration, insufficient feeding, inadequate breast milk, or the baby having fewer and less smooth bowel movements, which can lead to physiological jaundice that also fades slowly. However, for physiological jaundice, it generally does not last more than four weeks in preterm infants and no more than two weeks in full-term infants. If the newborn's jaundice persists longer and fades slowly, pathological causes should be considered, such as whether it is due to hemolytic disease, neonatal infection, infant hepatitis, or biliary atresia.

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Written by Li Jiao Yan
Neonatology
2min 14sec home-news-image

Causes of neonatal jaundice

Neonatal jaundice is generally divided into physiological jaundice and pathological jaundice. Physiological jaundice is usually considered a normal phenomenon, where the baby's jaundice can naturally recede without much impact on the baby. If it is pathological jaundice, it means that the jaundice level is high, indicating a pathological condition. Pathological jaundice can be further divided into several types, the most common being elevated direct bilirubin and elevated indirect bilirubin, each with different causes. Common causes of jaundice include increased indirect bilirubin due to infections, hemolysis, and mother-infant blood type incompatibility, such as ABO incompatibility where the mother is type O and the baby is not, or the mother has HR-negative blood and the baby has HR-positive blood. Other factors include reduced thyroid function, enzyme deficiencies such as G6PD deficiency, various types of bleeding like gastrointestinal bleeding, intracranial bleeding, or asphyxia at birth. Conditions like hypoxia or acidosis in the baby can also lead to increased jaundice. Additionally, liver function damage due to viral infections like hepatitis B, cytomegalovirus, and other infectious diseases such as syphilis, as well as other viruses like rubella virus and herpes virus can elevate jaundice levels. Developmental abnormalities of the biliary tract, commonly biliary atresia or congenital bile duct dilation, can cause elevated conjugated bilirubin levels. The causes of jaundice are complex, and some causes might remain unidentified. However, if the baby's general condition is good and the jaundice is manageable, it generally does not affect the baby. If jaundice levels are high, it is advised to visit a hospital where doctors can conduct relevant tests based on the baby's specific condition to determine if treatment is needed.

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Written by Li Jiao Yan
Neonatology
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Do newborns with jaundice need to be hospitalized?

Neonatal jaundice is one of the common symptoms in newborns, especially in premature newborns. It can either be a normal developmental symptom or an indication of certain diseases. In severe cases, it can lead to brain damage. Generally, about 80% of full-term newborns show visible signs of jaundice under normal conditions. However, it is crucial to differentiate between physiological and pathological jaundice. Physiological jaundice generally does not require intervention. If it is pathological jaundice, timely intervention and treatment are necessary because it can be an indication of various diseases. Without timely intervention, the baby might develop other serious complications. The most severe cases can see a continuous increase in bilirubin levels that might enter the brain, leading to kernicterus, and even cause hearing loss, possibly endangering life. Generally, if jaundice persists for a longer time, progresses rapidly, and is severe, it is crucial to seek medical attention promptly. If it is pathological jaundice, hospitalization for timely treatment is necessary. Neonatal jaundice is a critical indicator that requires close attention and monitoring.

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Written by Li Jiao Yan
Neonatology
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What is considered high for neonatal jaundice?

Neonatal jaundice is common during the neonatal period and can be divided into physiological jaundice and pathological jaundice. Physiological jaundice does not require intervention or treatment, and the baby's condition is generally okay. For physiological jaundice, the bilirubin level typically does not exceed 6 within the first 24 hours after birth, then not exceeding 9 from 24 to 48 hours, not exceeding 12 from 48 to 72 hours, and not exceeding 15 after 72 hours. If the monitored bilirubin levels exceed these ranges, there may be pathological jaundice, indicating abnormally high levels.

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Written by Li Jiao Yan
Neonatology
1min 10sec home-news-image

Newborn jaundice, how long does it fade?

Neonatal jaundice is one of the common symptoms during the neonatal period. It can be a normal physiological phenomenon, or it may be an external manifestation of certain diseases. Neonatal jaundice is divided into physiological jaundice and pathological jaundice. Physiological jaundice does not require intervention, and the baby's general condition is still acceptable. Typically, physiological jaundice in full-term infants appears between two to three days after birth, peaks at four to five days, and subsides around ten days, generally not lasting more than two weeks. In preterm infants, it may last slightly longer, but generally, jaundice does not exceed four weeks. If the progression of jaundice is rapid, severe, or appears early, pathological jaundice might be considered. Pathological jaundice may be due to certain pathological factors causing abnormal jaundice. Depending on the cause of the disease and whether there is timely intervention and treatment for jaundice, the resolution time may also vary.