neonatal jaundice subsidence time

Written by Li Jiao Yan
Neonatology
Updated on September 01, 2024
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Neonatal jaundice is a common phenomenon and a unique condition in newborns. If it is normal physiological jaundice, it generally subsides within two weeks for full-term infants born after 37 weeks. This means that after two weeks, the jaundice is essentially gone; the skin and eyes are no longer yellow, and bilirubin levels are typically below 6-7, which is considered normal. For premature infants, the jaundice generally clears within four weeks. If the jaundice persists longer, there might be some pathological factors involved, and it is advisable to visit a hospital for a thorough evaluation by a doctor to determine if any special treatment is needed.

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Written by Li Jiao Yan
Neonatology
1min 40sec home-news-image

What to do with neonatal jaundice?

Neonatal jaundice is the most common disease in newborns, mainly characterized by yellowing of the skin. Generally, normal babies also exhibit jaundice, but this is a type of physiological jaundice. If the baby's jaundice appears early, such as within twenty-four hours, or if the jaundice progresses rapidly with significantly rising jaundice levels, or if it is particularly severe, or if the jaundice lasts for a long duration, or if the jaundice recurs after fading, these are considered pathological jaundice. It is generally advised for pathological jaundice to consult a neonatal specialist for a detailed examination of the baby to determine whether treatment intervention is necessary. If the jaundice is severe and parents are worried, it is recommended to go to the hospital in a timely manner, as hospitalization for treatment may be needed. If the jaundice level is too high and there are some pathological factors, and parents are unable to observe the baby well and the baby's condition is not good, and the jaundice continues to rise, it could potentially progress to the brain, leading to bilirubin encephalopathy, which is a serious complication. Therefore, high jaundice levels still require timely intervention. If the jaundice is at its peak, it is recommended to test for jaundice daily, as timely intervention when jaundice levels are high can prevent serious complications.

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Written by Li Jiao Yan
Neonatology
1min 16sec home-news-image

Neonatal jaundice symptoms

Neonatal jaundice is most commonly seen in the skin and mucous membranes, and the sclera, or what we refer to as the eyes, presenting with a yellow discoloration of the white part. The most common symptom is yellowing of the skin. There may also be other symptoms such as crying and restlessness, fever, or rapid and irregular breathing. Some babies might sleep longer than usual, have difficulty feeding, or experience issues with bowel movements, such as a significant decrease in stool frequency or a reduction in urine output. These could be accompanying symptoms of neonatal jaundice. Each baby presents differently with jaundice; more accompanying symptoms often indicate a more severe condition. If the jaundice is limited to skin discoloration without other significant symptoms, it may indicate an early stage of the condition. Generally, if the jaundice is pronounced, it is considered pathological jaundice, and it is advisable to go to the hospital. A pediatric specialist can conduct relevant examinations and decide if immediate intervention and treatment are necessary.

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Written by Li Jiao Yan
Neonatology
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Causes of neonatal jaundice

Neonatal jaundice is generally divided into physiological jaundice and pathological jaundice. Physiological jaundice is usually considered a normal phenomenon, where the baby's jaundice can naturally recede without much impact on the baby. If it is pathological jaundice, it means that the jaundice level is high, indicating a pathological condition. Pathological jaundice can be further divided into several types, the most common being elevated direct bilirubin and elevated indirect bilirubin, each with different causes. Common causes of jaundice include increased indirect bilirubin due to infections, hemolysis, and mother-infant blood type incompatibility, such as ABO incompatibility where the mother is type O and the baby is not, or the mother has HR-negative blood and the baby has HR-positive blood. Other factors include reduced thyroid function, enzyme deficiencies such as G6PD deficiency, various types of bleeding like gastrointestinal bleeding, intracranial bleeding, or asphyxia at birth. Conditions like hypoxia or acidosis in the baby can also lead to increased jaundice. Additionally, liver function damage due to viral infections like hepatitis B, cytomegalovirus, and other infectious diseases such as syphilis, as well as other viruses like rubella virus and herpes virus can elevate jaundice levels. Developmental abnormalities of the biliary tract, commonly biliary atresia or congenital bile duct dilation, can cause elevated conjugated bilirubin levels. The causes of jaundice are complex, and some causes might remain unidentified. However, if the baby's general condition is good and the jaundice is manageable, it generally does not affect the baby. If jaundice levels are high, it is advised to visit a hospital where doctors can conduct relevant tests based on the baby's specific condition to determine if treatment is needed.

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Written by Li Jiao Yan
Neonatology
1min 16sec home-news-image

Do newborns with jaundice feel uncomfortable?

Neonatal jaundice is one of the most common symptoms during the newborn period. It can be a normal physiological phenomenon occurring in the baby's development process, or it may indicate some diseases. Neonatal jaundice is divided into physiological jaundice and pathological jaundice. Generally, the degree of jaundice in physiological jaundice is not very high, and the general condition is still okay. The baby does not show any special discomfort. However, if it is pathological jaundice, the jaundice usually lasts longer and progresses faster with a more severe degree. There might be other discomforts, such as obvious crying and restlessness, possibly even fever, and other symptoms like sleepiness or refusal to feed. Therefore, if the jaundice is slightly high, the general condition is still manageable, and parents should not worry too much. However, if there are obvious discomforts, it is recommended to visit the hospital promptly because if a newborn baby gets sick and is not treated in time, the condition can progress quickly.

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Written by Li Jiao Yan
Neonatology
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When does neonatal jaundice completely disappear?

Neonatal jaundice is one of the most common conditions in newborns. Due to the metabolic characteristics of bilirubin in newborns, about 50%-60% of full-term infants and 80% of preterm infants experience jaundice. Jaundice is categorized into physiological jaundice and pathological jaundice. If it is physiological jaundice, the duration typically does not exceed two weeks in full-term infants, and in preterm infants, it can extend up to three to four weeks, generally not exceeding four weeks. If the jaundice progresses quickly and is severe, and if its resolution is delayed, there might be an underlying pathological jaundice. Pathological jaundice may involve certain pathological factors, necessitating a hospital visit. Based on the baby’s specific conditions, targeted examinations should be conducted, and treatment should focus on the underlying cause to actively manage the jaundice. The length of time jaundice takes to resolve may vary depending on the cause or the condition of the baby. How the jaundice subsides depends on the condition. If pathological jaundice is not promptly managed, the severity of the jaundice may increase, and there may be a risk of severe complications. Therefore, if the jaundice level is high and parents are unsure, it is advised to have it checked at a hospital. If pathological jaundice is confirmed, timely intervention and treatment are necessary.