Neurodermatitis, also known as chronic simple lichen, is a common chronic inflammatory skin disease characterized by episodic severe itching and lichenoid skin changes. The characteristic skin lesions mainly consist of polygonal, flat papules that range in color from pale red, pale brown to normal skin tone. They are relatively hard and shiny with a small amount of scale on the surface. Over time, the lesions can merge into plaques, and the local skin becomes thickened and rough with lichen-like changes. Therefore, in clinical practice, various topical medications are rationally used based on the characteristics, types, and locations of these lesions. The common types of topical medications include glucocorticoid ointments, tar ointments, and moisturizing antipruritic ointments. Commonly used medications include hydrocortisone butyrate ointment, desonide ointment, mometasone furoate ointment, halometasone ointment, fluticasone propionate ointment, 10% black soybean distillate ointment, 5%-10% Konju butter or coal tar ointment, pine distillate ointment, urea vitamin E ointment, etc.