Neurodermatitis is a common chronic inflammatory skin disease characterized by paroxysmal severe itching and lichenoid changes in the skin. If neurodermatitis occurs during breastfeeding, we should go to the hospital. Firstly, avoid scratching, friction, and other irritations, maintain a peaceful mindset, wear cotton clothing, and reduce localized stimulations. Diet-wise, intake of alcohol should be reduced, as well as spicy and irritating foods, and one should avoid eating shellfish, seafood, and other potentially aggravating foods. Secondly, appropriate topical medications should be used, such as moisturizing anti-itch ointments and traditional Chinese medicine ointments, and the use of corticosteroid ointments should be minimized. Thirdly, try not to take oral medications.