How long does it take for cervical cancer to develop?

Written by Xu Xiao Ming
Obstetrics and Gynecology
Updated on December 17, 2024
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The causes of cervical cancer are now clear; it is caused by an infection with the HPV virus. Generally, this virus needs to be carried for more than two to three years before it can infect and develop into cervical cancer. There is a process of carcinogenesis where normal epithelial tissue transforms into cervical intraepithelial neoplasia. If the HPV infection is not treated and continues, it could lead to cervical cancer. Thus, the development process is relatively long, typically requiring two to three years. It is recommended that sexually active women undergo cervical cancer screening to check for any pathological changes in the cervix, including HPV, TCT, and colposcopy examinations.

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Written by Yan Qiao
Obstetrics and Gynecology
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Does cervical cancer hurt?

For patients with cervical cancer, the most common clinical manifestations are bleeding during sexual intercourse and irregular vaginal bleeding. Patients who have undergone menopause may also experience irregular vaginal bleeding post-menopause, and some patients may not show any clinical signs at a very early stage. As the cancer progresses, and when it invades nearby organs and metastasizes, it may cause lower abdominal distension and pain, and even more severe pain if the metastatic organs compress nerves or directly invade areas containing nerves.

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Written by Zhang Xiu Rong
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How long does it take for cervical cancer to develop?

Cervical cancer generally forms beginning with an infection of human papillomavirus (HPV), and it usually takes five to ten years to develop into cervical cancer. The vast majority of cervical cancer cases are caused by contact with HPV. If this virus continues to replicate in the body, it typically progresses to cervical cancer over a period of five to ten years. Therefore, cervical cancer screening is crucial for women. If regular check-ups are performed annually during this period, it is possible to halt the progression to cervical cancer and its precursors. Cervical cancer screening generally includes routine TCT (ThinPrep Cytologic Test) and HPV testing. These two tests can preliminarily screen for cervical cancer and precancerous conditions. If any abnormalities are detected, it is essential to undergo a colposcopic biopsy at a hospital, as biopsy is the gold standard for diagnosis.

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Written by Gong Chun
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Staging of cervical cancer

The clinical staging of cervical cancer mainly uses the FIGO system, which adopts the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO). Staging should be performed before treatment, and once done it does not change after treatment. Since FIGO staging of cervical cancer primarily relies on pelvic examination, it emphasizes the necessity of this examination being conducted by two experienced gynecologic oncologists. If needed, a pelvic examination under anesthesia is performed to ensure the accuracy of the evaluation. So, how is the staging performed? It involves measuring the size of the cervical lesion, particularly the measurement of endophytic tumors, the infiltration of cervical tissue, and the status of pelvic lymph nodes, providing accurate information with the aid of radiological data, especially magnetic resonance imaging (MRI).

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Written by Xu Xiao Ming
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Can cervical cancer be cured?

Cervical cancer can be treated with options including surgery, radiotherapy, and chemotherapy. For Stage 1A1 cervical cancer, a conization surgery can be chosen; for stages from 1A2 up to before 2B, a radical hysterectomy with bilateral adnexectomy and pelvic lymphadenectomy can be selected; if it is Stage 2B, where the cancer has spread to the parametrium, it is recommended to first undergo chemotherapy as preoperative neoadjuvant therapy to reduce the tumor size before proceeding with surgery; if the cancer has progressed to Stage 3A1 and beyond, radiotherapy or chemotherapy is recommended. In summary, surgical treatment can be chosen for cervical cancer before Stage 2B; if it is Stage 2B or later, involving the parametrium or the lower third of the vagina, surgery is generally not an option, and the treatment usually involves radiotherapy or chemotherapy.

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Will the cervix rot in the late stages of cervical cancer?

In late-stage cervical cancer, some patients experience severe local tumor infiltration which can lead to tissue necrosis. This necrosis often leads to secondary infections, thereby causing severe complications such as septic shock. In treating such patients, in addition to administering anti-tumor therapies, the primary treatment involves the use of antibiotics to control the infection, to prevent potentially fatal complications such as septic shock. Furthermore, the disease in most patients with late-stage cervical cancer typically presents as widespread dissemination. This dissemination is primarily manifested by metastasis to distant lymph nodes and infiltration of surrounding tissues, as well as metastasis to remote organs like the lungs, liver, and other abdominal organs. Clinically, patients mainly exhibit symptoms related to these metastatic sites.