Chronic atrophic gastritis has a certain chance of cancerous transformation, with an annual cancer transformation rate of between 0.5% and 1%. It is a type of chronic gastritis. During gastroscopy, the atrophy of the inherent glands of the gastric mucosa can be observed. A definitive diagnosis of chronic atrophic gastritis can be made through biopsy and pathological examination. In terms of treatment, the first step is the treatment against Helicobacter pylori, which includes a proton pump inhibitor, two antibiotics, and a bismuth agent, with a treatment course of 14 days. Additionally, treatments include acid suppression, stomach protection, promoting gastric motility, and protecting the gastric mucosa. Furthermore, oral traditional Chinese medicine plays a significant role in the treatment of atrophic gastritis. Therefore, it is suggested that patients with atrophic gastritis consider integrated traditional Chinese and Western medicine treatment, which can yield good results.