Primary liver cancer causes

Written by Liu Liang
Oncology
Updated on January 20, 2025
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The causes and specific mechanisms of primary liver cancer are not yet very clear; its development is a complex process involving multiple factors and steps, influenced by various aspects such as environment and diet. Primary liver cancer is associated with chronic hepatitis B and C virus infections, aflatoxin, contaminated drinking water, and alcoholic cirrhosis, among other factors. Particularly, hepatocellular carcinoma has a significant association with hepatitis B, and most patients may also have a history of chronic hepatitis B.

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The difference between primary liver cancer and metastatic liver cancer

Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to cancers that start in other parts of the body and then spread to the liver through lymphatic and blood circulation, among other routes. Another difference is that primary liver cancer is more likely to be a single lesion, while metastatic liver cancer generally involves multiple lesions. Regarding the differences between primary and metastatic liver cancer, their treatment methods also differ. For primary liver cancer, interventional chemotherapy or surgery, such as hepatic lobectomy, can be performed if the tumor is small. In contrast, metastatic liver cancer usually involves multiple lesions, making surgery alone challenging. Additionally, the primary tumor also requires treatment.

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Which is more treatable, primary liver cancer or metastatic liver cancer?

Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to malignant tumors from other parts of the body that have spread to the liver. As to which is easier to treat, it is generally difficult to determine and depends on the control of the primary lesion in cases of metastatic liver cancer; both might be challenging to treat. However, if the lesion in primary liver cancer is relatively small, there may still be an opportunity for surgical treatment. In general, metastatic liver cancer is not amenable to curative surgery because the primary lesion also requires treatment. But in terms of the rate of progression or severity, metastatic liver cancer might progress more slowly, while primary liver cancer generally progresses quite rapidly, making it also very difficult to treat.

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Written by Yan Chun
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Why can't people with liver cancer drink milk?

Liver cancer patients are generally advised not to drink milk, particularly in cases of advanced liver cancer where there is a potential for hepatic encephalopathy. This is because, for patients in the late stages of liver cancer, liver function is compromised, and some may already exhibit symptoms indicative of pre-hepatic encephalopathy. Consuming a diet rich in protein can easily trigger hepatic encephalopathy, and since milk is high in protein, its consumption is usually limited or avoided in such patients. However, for the majority of liver cancer patients, drinking milk is permissible as it not only contains abundant protein but also rich calcium, which is beneficial for the recovery of liver cancer patients. Most liver cancer patients have hypoalbuminemia (low levels of protein in the blood) and some also have hypocalcemia (low levels of calcium in the blood), thus the intake of calcium and protein-rich foods can be very beneficial for their recovery.

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Is primary liver cancer hereditary?

Primary liver cancer is usually not hereditary, but the reason why it tends to appear in families in China is mainly due to the widespread infection of hepatitis B virus, which then leads to a significant correlation with hepatic cirrhosis caused by hepatitis B. It is well known that the hepatitis B virus is contagious and can easily be transmitted within families and from mother to child. Therefore, it is not uncommon to see several cases of liver cancer within the same family, indicating a familial aggregation. Another factor is related to dietary habits, for example, the infection of aflatoxin, which is mainly found in moldy peanuts. If the dietary habits within a family are similar, then, of course, the likelihood of occurrence is certainly higher.

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What changes occur in the hair during the early stages of liver cancer?

Liver cancer is a common type of tumor in the digestive system in China, and patients with early-stage liver cancer generally do not experience significant changes in their hair. This is because the tumors in early-stage liver cancer patients are relatively small, and the treatment often involves surgical removal, which does not require chemotherapy or other anti-tumor treatments, so the impact on the patient's hair is minimal. As the disease progresses, some patients may need to undergo chemotherapy or other anti-tumor treatments, which can lead to hair loss or changes in hair color. However, hair changes after chemotherapy in liver cancer patients are generally reversible, and hair can regrow after the end of chemotherapy. Changes in hair color, on the other hand, are generally caused by pigment deposition induced by some chemotherapy drugs.