Will "small three yang" lead to liver cancer?

Written by Ye Xi Yong
Infectious Diseases
Updated on September 03, 2024
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Hepatitis B "minor three positives" refers to positivity in the first, fourth, and fifth items of the complete hepatitis B panel. It is common among patients with acute and chronic hepatitis B. There is no necessary correlation between "minor three positives" and cancer. While some patients with "minor three positives" may develop liver cancer, not all liver cancer patients necessarily progress from this condition, indicating no inevitable link between the two.

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Written by Liu Liang
Oncology
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Common symptoms of primary liver cancer

The initial symptoms of primary liver cancer are mostly pain in the liver area, which commonly presents as abdominal pain. Some patients may also experience bloating, fatigue, and weight loss as systemic symptoms. In advanced-stage liver cancer patients, there can be an enlargement of the liver, meaning a palpable enlarged mass can be felt in the abdomen. Other symptoms include jaundice and ascites, which can cause abdominal bloating. Upon physical examination, an obvious increase in abdominal girth and abdominal distension can be noted. Moreover, patients with advanced liver cancer may also suffer from complications such as upper gastrointestinal bleeding, rupture and bleeding of the liver cancer nodules, liver failure, and even hepatic encephalopathy, among others.

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Written by Yan Chun
Oncology
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Will people with early-stage liver cancer experience weight loss?

Patients with early-stage liver cancer generally do not experience weight loss; weight loss is more commonly a clinical manifestation in patients with late-stage liver cancer. The reason for weight loss in liver cancer patients is due to the damage caused by cancerous tissue to liver function, leading to reduced synthesis of albumin. Furthermore, patients with liver cancer often experience a significant decrease in food intake, resulting in insufficient intake of nutrients such as albumin. Additionally, the progression of liver cancer tumors requires the consumption of a large amount of the body's albumin. Therefore, due to these factors, many patients with late-stage liver cancer exhibit clinical manifestations of weight loss. Moreover, besides not experiencing weight loss, patients with early-stage liver cancer also do not typically present with typical clinical symptoms. Many patients are asymptomatic, and as the lesion progresses, the cancer spreads, possibly leading to clinical manifestations associated with tumor spread. For example, pain in the liver area, a significant decrease in food intake, fatigue, fever, pain, and some patients may also exhibit symptoms of metastasis such as headaches, vomiting, abdominal pain, and abdominal distension.

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Written by Si Li Li
Gastroenterology
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Can hepatitis B turn into liver cancer?

Hepatitis B can gradually develop into cirrhosis or liver cancer. Therefore, if a hepatitis B virus infection is detected, it needs attention. If the hepatitis B surface antigen is positive in the HBV "two-and-a-half" test, it indicates a hepatitis B virus infection. Once infected with the hepatitis B virus, it is necessary to regularly check liver function and hepatitis B virus DNA, as well as have abdominal ultrasounds. If an increase in transaminases is found, it indicates the transformation into chronic hepatitis B, necessitating liver-protecting and enzyme-lowering treatments. If the hepatitis B virus DNA exceeds a certain value, antiviral treatment is also needed. After being infected with the hepatitis B virus, it is crucial to rest and avoid excessive fatigue and staying up late.

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Written by Du Ning
Hepatobiliary Surgery
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Can gallbladder stones turn into liver cancer?

Long-term pathological changes from hepatobiliary calculi can lead to liver cancer. Hepatobiliary calculi generally refer to intrahepatic bile duct stones. When these stones grow in a single duct and gradually increase in number and size, they can cause obstruction of the bile duct. Obstruction of the bile duct subsequently leads to cholangitis, which involves repeated inflammatory irritation. This, in turn, can cause malignant transformation of the bile duct cells. Following this transformation, a tumor forms, which can develop into cholangiocellular carcinoma, a type of liver cancer. Therefore, if intrahepatic bile duct stones cause long-term inflammatory stimulation, it can lead to cancerous changes and result in liver cancer. Thus, if intrahepatic bile duct stones have already caused noticeable clinical symptoms such as abdominal pain, fever, and liver function abnormalities, aggressive surgical treatment should be considered.

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Written by Wu Hai Wu
Gastroenterology
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Does liver palm mean liver cancer?

Liver palm is not liver cancer; it is a clinical symptom caused by the stage of liver cirrhosis in patients. Once liver palm appears, it is important to pay attention and visit the gastroenterology or hepatology department of a standard hospital for a complete liver function test and upper abdominal imaging to confirm the diagnosis of the disease. Depending on the specific diagnosis, appropriate treatment measures should be taken. If liver palm is caused by alcoholic liver disease leading to cirrhosis, active abstinence from alcohol is necessary. If it is caused by viral hepatitis, antiviral treatment is required, along with active liver-protective treatment.