How many days does it take to be discharged from the hospital for Kawasaki disease?

Written by Li Jiao Yan
Neonatology
Updated on September 04, 2024
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Kawasaki disease is a disease with unclear pathogenesis and etiology. A major pathological change is systemic vasculitis, which commonly affects the coronary arteries. Typically, it presents with fever lasting from seven to fourteen days or longer, and antibiotics are ineffective in treatment. During the first through sixth weeks of the illness, complications such as pericarditis, myocarditis, endocarditis, and arrhythmias may occur. Coronary artery damage often occurs between the second and fourth weeks of the illness, and proactive and effective treatment of Kawasaki disease can prevent coronary complications. The acute phase generally involves symptomatic supportive care, prevention of platelet aggregation, fever reduction, and prevention of coronary artery damage. Treatment with intravenous immunoglobulin is recommended within the first ten days of onset. If the treatment is not effective, other special medications like steroids may be used, and the treatment duration is generally between two to four weeks. Thus, the pathogenesis of Kawasaki disease is uncertain, and its pathological process is prolonged. The specific timing of discharge depends on the child's condition. If the fever is controlled and no significant coronary artery damage is evident, and the condition is stable, then discharge is possible. However, post-discharge, follow-up should be conducted based on the child's specific condition. Therefore, the duration of hospitalization for Kawasaki disease is not fixed and depends on the child's condition and treatment response.

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Written by Shi Ji Peng
Pediatrics
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How long does Kawasaki disease require hospitalization?

Kawasaki disease requires hospitalization and continued medication after discharge. The duration of the hospital stay is mainly determined by the child's clinical symptoms. The child can return home when the fever subsides and the dosage of aspirin is reduced, which may take about four to seven days, although this is just a general scenario. After discharge, medication must continue. If the child's coronary arteries are fine, with no dilation or lesions, a low dose of aspirin can be taken for about two months. If there are issues with the coronary arteries, aspirin must be continuously taken until the dilation resolves before stopping the aspirin, so this period can be quite long.

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Written by Li Jiao Yan
Neonatology
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Does Kawasaki disease cause coughing?

Kawasaki disease has an unclear pathogenesis, primarily manifesting as systemic vasculitis, frequently affecting the coronary arteries. Clinically, it is characterized by fever, typically a high fever lasting seven to fourteen days, and is unresponsive to antibiotic treatment. Other symptoms include conjunctival congestion, cracked lips, diffuse oral congestion, and strawberry tongue. In the acute phase, there might be hard edema and erythema development, with polymorphous erythema and scarlatiniform rash typically on the trunk. Additionally, unilateral or bilateral cervical lymphadenopathy with tenderness can occur. Generally, coughing is rare and may be due to other infections like upper respiratory infections in children with weaker immunity.

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Written by Yao Li Qin
Pediatrics
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Kawasaki disease incubation period

Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a common pediatric fever and rash illness, primarily a systemic small vessel vasculitis. Kawasaki disease is not contagious, so it has no incubation period; only infectious diseases have incubation periods. If it were contagious, typical manifestations would include persistent high fever, pinpoint appearances around the eyes and mouth, typical rash, swelling of the hands and feet, and non-purulent swelling of the cervical lymph nodes. Therefore, Kawasaki disease has no incubation period and is a vasculitis mediated by immune mechanisms.

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Written by Shi Ji Peng
Pediatrics
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Kawasaki Disease Aspirin Side Effects

Aspirin is necessary for Kawasaki disease. Considering the pros and cons, aspirin must be used in cases of Kawasaki disease, initially in high doses. However, aspirin indeed has side effects. Some say aspirin is contraindicated for children, as its consumption can lead to Reye's Syndrome. This syndrome involves widespread mitochondrial damage following the intake of salicylate drugs during viral infection recovery, posing risks to the liver and brain. Without timely treatment, it could likely lead to liver and kidney failure, brain damage, or even death. Thus, aside from specific diseases, the use of aspirin is strictly prohibited. These specific diseases include Kawasaki disease, rheumatoid arthritis, etc. Therefore, the use of aspirin in Kawasaki disease is necessary, but it can indeed lead to some side effects.

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Written by Li Jiao Yan
Neonatology
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Is it normal for Kawasaki disease to have a lower temperature?

The etiology of Kawasaki disease is currently unclear; its primary pathological feature is systemic vascular inflammation. Kawasaki disease typically presents with fever, high fevers ranging from 39 to 40 degrees Celsius. If a patient with Kawasaki disease has a lower temperature, it may indicate that the condition is quite severe. For example, children generally have weaker immune systems, or if they have a severe co-infection, hypothermia may occur. In this case, it is recommended that doctors perform further examinations and intensify treatment. Therefore, a lower temperature in Kawasaki disease is also abnormal. Normally, the body temperature should gradually return to the normal range, and both hypothermia and hyperthermia are definitely abnormal conditions.