The difference between rickets and dwarfism.

Written by Zeng Hai Jiang
Pediatrics
Updated on November 21, 2024
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Rickets is caused by a deficiency of vitamin D in infants and young children, leading to disturbances in calcium and phosphorus metabolism and resulting in skeletal abnormalities as a characteristic of this chronic nutritional disease. Typical symptoms can include changes in the bones, especially in the fastest growing parts of the skeleton, and can affect muscle development and changes in neural excitability. Symptoms such as a "ping pong ball" head, square skull, pigeon chest, funnel chest, and eversion of the rib margins are also observed. Diagnosis is made through examinations such as vitamin D levels and skeletal X-rays. Dwarfism, on the other hand, is a growth disorder caused by a deficiency of growth hormone from the anterior pituitary gland before puberty. Its clinical manifestations are primarily growth disturbances, characterized by a short, proportionate stature. Adults with this condition often retain a child-like appearance, and their bone development is delayed with bone age younger than their chronological age. Intellect corresponds to their age, and sexual development may also be disrupted.

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The main manifestations of rickets in the early stage

Rickets generally refers to vitamin D deficiency rickets, mainly due to insufficient vitamin D in children, leading to calcium and phosphorus metabolism disorders. It is a chronic nutritional disease characterized by skeletal lesions. The main manifestations are changes in the fastest growing parts of the skeleton, which can also affect muscle development and changes in neural excitability. The initial symptoms of rickets are common in infants, especially those under three months old. The main symptom is increased neural excitability; the child is particularly prone to being agitated, irritable, crying, sweating, and shaking their head due to scalp stimulation, but these are not specific symptoms of rickets. Therefore, blood tests are still necessary in the early stages, showing decreased levels of 25-hydroxyvitamin D3, blood calcium, and blood phosphate, increased PTH, normal or slightly elevated alkaline phosphatase activity, and normal or slightly blurry calcification zones in skeletal X-rays. These are the early manifestations of rickets.

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How is rickets treated with injections?

Rickets, also known as vitamin D deficiency rickets, is a chronic nutritional disease characterized by skeletal lesions, caused by insufficient vitamin D in children, leading to disturbances in calcium and phosphorus metabolism. The typical manifestation of rickets is incomplete mineralization of the growing long bone epiphyses and bone tissue, presenting as bone softening or deformity. Once rickets is diagnosed, it must be treated aggressively. First, children are given high doses of vitamin D, either orally or through intramuscular injection, with a common practice of administering a single dose of 300,000 units of vitamin D intramuscularly. A month later, a blood sample is taken to measure the vitamin D content; if it is below normal, treatment must continue; if it is within the normal range, it is only necessary to supplement the daily physiological requirement of vitamin D for the child. (Specific medication should be administered under the guidance of a physician.)

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Can rickets be cured?

Rickets is a chronic nutritional disease caused by vitamin D deficiency that leads to disturbed calcium and phosphorus metabolism in the body, causing abnormal skeletal development. If a square skull is observed, it indicates that the child's disease has entered an active phase. Generally, in the early stages, there is an enlargement of the fontanelle or a delay in the closure of the fontanelle. By seven to eight months, a square skull can appear, primarily characterized by outward bulging centered on the frontal and parietal bones. At this time, it is generally necessary to administer a sufficient dose of vitamin D and encourage appropriate outdoor activities. Depending on the child's condition, it might be appropriate to supplement with calcium as well. Gradually, this should be curable; however, if there are other special causes for the abnormal vitamin D levels, such as severe liver or kidney disease or some new genetic diseases causing square skull, the treatment might be more challenging.

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Can rickets be cured?

Rickets refers to a nutritional disease characterized by bone lesions caused by disorders in calcium and phosphorus metabolism due to a deficiency of vitamin D in the body. The primary treatment for rickets involves early detection and comprehensive treatment at an early stage, which is crucial. The general treatment goal is to control the active phase, prevent deformities, and avoid recurrence. Nutritional rickets due to a deficiency of vitamin D is a self-limiting disease; it can be cured once infants and young children engage in sufficient outdoor activities and supplement with vitamin D. Early detection of low vitamin D levels or abnormalities in calcium and phosphorus metabolism, along with early proactive intervention, can prevent the occurrence of skeletal deformities. If sequelae are present, there is no need for medication; mild to moderate cases should strengthen physical exercise, and skeletal deformities can be corrected through active or passive rehabilitation movements. Severe skeletal deformities can be corrected through surgical treatment.

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Should I take vitamin D or D3 for rickets?

Rickets should be treated with D3, but strictly speaking, what we commonly refer to as vitamin D is D3, just phrased differently. Vitamin D3 helps promote the absorption of calcium by bones, preventing the occurrence of rickets symptoms. The main clinical manifestations of rickets appear in the deformation of bones, such as square skull, pigeon chest, flaring ribs, X-shaped legs, O-shaped legs, and other changes in bone status. The nervous system can show symptoms such as night sweats, nervous excitability, balding at the back of the head, poor sleep quality, and easiness to cry. For rickets, it is necessary to diagnose early, timely supplement with vitamin D to prevent symptoms from worsening, and also to get more sunlight and engage in outdoor activities, which helps the body synthesize vitamin D and absorb calcium.