What are the early symptoms of Helicobacter pylori infection?

Written by Si Li Li
Gastroenterology
Updated on February 19, 2025
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Helicobacter pylori can cause chronic gastritis, peptic ulcers, and even stomach cancer. Infection with Helicobacter pylori may result in symptoms such as upper abdominal distension and pain, belching, acid reflux, nausea, vomiting, poor appetite, bad breath, and indigestion. A carbon-14 breath test can confirm a Helicobacter pylori infection. Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%. If an infection is present and symptoms or diseases of the digestive system occur, eradication treatment for Helicobacter pylori is necessary. The treatment regimen consists of a proton pump inhibitor, two types of antibiotics, and a bismuth agent, adjusted to a 14-day course.

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Written by Lian Wen Xi
Pediatrics
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What are the symptoms of children infected with Helicobacter pylori?

Children infected with Helicobacter pylori typically show no symptoms initially, but may later develop chronic gastritis and gastrointestinal ulcers. Clinical manifestations mainly include vomiting, nausea, abdominal distension, acid reflux, and abdominal pain, and may even present symptoms such as bloody stools or vomiting blood. If a child is infected with Helicobacter pylori but exhibits mild symptoms, treatment can focus solely on the infection. However, if there are gastrointestinal ulcers or repeated gastrointestinal discomfort, treatment should include antibiotics along with medications that suppress stomach acid production. Treatment duration usually lasts about one to two months, depending on the specific condition of the child.

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Written by Wu Hai Wu
Gastroenterology
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Why is there an increase in flatulence after the treatment of Helicobacter pylori?

After treatment for Helicobacter pylori, having more flatulence generally isn't directly related to the treatment, as the medication used includes proton pump inhibitors, antibiotics such as amoxicillin, clarithromycin, as well as bismuth citrate potassium. None of these drugs typically cause increased flatulence. If a patient experiences more flatulence after treatment, it might be due to functional dyspepsia. At this point, treating the condition with medications that regulate the gut flora, such as combined lactobacilli and Bifidobacterium triple live bacteria, might be effective. If the increased flatulence persists, it is advisable to promptly undergo a digital colonoscopy to rule out the possibility of organic intestinal diseases. (Specific medications should be used under the guidance of a doctor.)

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Written by Jiang Guo Ming
Gastroenterology
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What are the symptoms of Helicobacter pylori infection?

Helicobacter pylori is a pathogen produced in the stomach or oral cavity. It cannot be said that Helicobacter pylori causes any specific symptoms, rather, it is the infection of Helicobacter pylori that leads to a series of diseases presenting symptoms. Some people infected with Helicobacter pylori may not show any symptoms at all. If related diseases occur, such as gastritis or ulcers, symptoms such as acid reflux, heartburn, nausea, and vomiting may appear. Additionally, some patients, like those with refractory iron deficiency anemia or idiopathic thrombocytopenic purpura, may also have conditions associated with Helicobacter pylori infection.

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Written by Peng Miao Yun
Internal Medicine
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What should I do if I have a Helicobacter pylori infection?

Helicobacter pylori is closely related to the occurrence of chronic gastritis, gastric ulcers, and gastric cancer, but not everyone infected with Helicobacter pylori will develop chronic gastritis or gastric ulcers. Infections can be diagnosed with a breath test, where values more than twice the normal level, accompanied by symptoms of gastritis, gastric ulcers, stomach distension, stomach pain, and acid reflux, should be considered for antibacterial and stomach-protective treatment. Generally, with standard treatment, 90% of Helicobacter pylori can be eradicated within one to two weeks. However, reinfection is common as it can be found in food and utensils and transmitted through saliva. It is generally advised that children under 14 and individuals with low levels of Helicobacter pylori without obvious stomach inflammation symptoms do not require immediate treatment.

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Written by Wang Hui Jie
Gastroenterology
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Can a gastroscopy examine Helicobacter pylori?

Can a gastroscopy detect Helicobacter pylori? Helicobacter pylori is a type of bacteria, thus it cannot be seen with the naked eye. However, recent research shows that Helicobacter pylori is closely related to certain mucosal appearances observed under endoscopy. Therefore, endoscopists can infer the infection of Helicobacter pylori based on certain mucosal appearances. However, if a patient is just testing for Helicobacter pylori infection, there is no need for a gastroscopy. We can choose some non-invasive methods such as the carbon-13 breath test, carbon-14 breath test, stool antigen test, and serological antibody test, which are commonly used detection methods. Moreover, after treatment for Helicobacter pylori, it is recommended to choose the carbon-13 or carbon-14 breath test, as they are quite accurate.