During the treatment of Helicobacter pylori, there usually isn't significant discomfort, but a small number of patients may experience upper abdominal discomfort, nausea, vomiting, and other symptoms after taking antibiotics. Treatment of Helicobacter pylori requires a two-week quadruple therapy including a bismuth-containing agent. During the treatment of Helicobacter pylori infection, it is recommended to consume fresh vegetables and fruits rich in vitamins, avoid spicy and irritating foods, quit smoking and drinking, and avoid strong tea and coffee. Furthermore, it is advisable to avoid overeating and drinking excessively during the treatment period.