Is a gastroscopy examination accurate for detecting Helicobacter pylori?

Written by Yang Chun Guang
Gastroenterology
Updated on September 16, 2024
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Gastroscope testing for Helicobacter pylori is conducted under a gastroscope and is quite accurate. However, nowadays, if one is only testing for Helicobacter pylori, it generally does not require an endoscopic examination, since undergoing a gastroscope is an uncomfortable process that can cause nausea.

Currently, Helicobacter pylori can be detected using a breath test method involving carbon-13 or carbon-14. This involves swallowing a capsule and then performing a breath test. It is crucial to fast before the test, as eating can affect the accuracy of the results.

Therefore, although gastroscope testing for Helicobacter pylori is accurate, it is less commonly used nowadays.

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How long does Helicobacter pylori resistance last?

Helicobacter pylori resistance generally develops around two weeks. If Helicobacter pylori shows resistance, it is advisable to consider adjusting the treatment using other antibiotics. The eradication treatment for Helicobacter pylori infection generally involves a two-week quadruple therapy with a bismuth-containing regimen. Furthermore, one month after stopping the eradication treatment, it is necessary to recheck with a carbon-13 breath test or a carbon-14 breath test to confirm effective eradication. Helicobacter pylori infection can cause gastritis, peptic ulcers, and malignant tumors in the stomach, among other issues.

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Is Helicobacter pylori three pluses serious?

Three pluses for Helicobacter pylori indicate that there is an infection with Helicobacter pylori, and the level of infection is not low. Helicobacter pylori is the main cause of chronic gastritis, peptic ulcers, and even stomach cancer. If a person tests positive for Helicobacter pylori infection, and has symptoms or diseases related to the digestive system, or has a family history of stomach cancer, eradication treatment for Helicobacter pylori is necessary. The treatment involves a proton pump inhibitor plus two types of antibiotics, along with a bismuth agent, for a total of 14 days. After stopping the medication for one month, a carbon-14 breath test should be re-conducted. If the result turns negative, it means that the eradication treatment for Helicobacter pylori was successful. If it does not turn negative, remedial treatment is required.

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What are the symptoms of Helicobacter pylori infection?

Helicobacter pylori is a pathogen produced in the stomach or oral cavity. It cannot be said that Helicobacter pylori causes any specific symptoms, rather, it is the infection of Helicobacter pylori that leads to a series of diseases presenting symptoms. Some people infected with Helicobacter pylori may not show any symptoms at all. If related diseases occur, such as gastritis or ulcers, symptoms such as acid reflux, heartburn, nausea, and vomiting may appear. Additionally, some patients, like those with refractory iron deficiency anemia or idiopathic thrombocytopenic purpura, may also have conditions associated with Helicobacter pylori infection.

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Can you eat sweets during the treatment for Helicobacter pylori?

During the treatment of Helicobacter pylori, it is permissible to eat sweets. During this period, it is necessary to avoid spicy and irritating foods, as well as avoid drinking strong alcohol, strong tea, coffee, and so on. It is recommended to consume more fresh vegetables and fruits rich in vitamins, as well as nutritious and light foods. Smoking and drinking alcohol should be avoided, and meals should be regular and in measured quantities. Since sweet foods are not considered spicy or irritating, they can be consumed during the treatment of Helicobacter pylori. After the treatment of a Helicobacter pylori infection, it is necessary to wait one month after stopping the medication before a follow-up examination to confirm whether the bacteria have been completely eradicated.

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Do normal people have Helicobacter pylori?

In my understanding, a “normal person” refers to individuals who do not experience any stomach discomfort. In our country, the infection rate of Helicobacter pylori is extremely high, with reports indicating that over 50% of adults are infected, albeit asymptomatically. Thus, it is certain that many so-called "normal people" are infected with Helicobacter pylori, also known as asymptomatic Helicobacter pylori carriers. This condition also requires antibacterial treatment because there is a close relationship between Helicobacter pylori and gastritis, ulcers, and gastric cancer. Even for patients with chronic superficial gastritis, if Helicobacter pylori is present, eradication therapy is advocated. If not completely eradicated, it often leads to the development of chronic atrophic gastritis, which is a more serious condition.