Patients with pericardial effusion should not smoke; in cases where there is a significant amount of pericardial fluid, it often leads to reduced heart pumping, resulting in ischemia and hypoxia, and causing symptoms such as difficulty breathing, palpitations, chest tightness, fatigue, and limb swelling. Smoking stimulates the sympathetic nervous system, leading to an increased heart rate and may exacerbate symptoms of ischemia and hypoxia. Severe cases may even trigger acute heart failure or induce pericardial effusion. In addition to not smoking, patients should also abstain from alcohol. Moreover, dietary recommendations include avoiding greasy foods and overeating, and patients should avoid excessive physical exertion. Poor lifestyle habits are often a significant factor in the worsening of pericardial effusion symptoms.