The relationship between the two is not very significant. A ventricular septal defect is a type of congenital disease, and currently, surgical treatment is recommended for patients, as medical treatment is not very effective and prone to relapse. For this type of congenital heart disease, it is best to first perform a cardiac echocardiography to make a clear diagnosis. In terms of treatment, early surgical intervention is suggested for patients to thoroughly improve symptoms such as palpitations, chest tightness, and difficulty in breathing. If an infant often experiences hiccupping, it could be a sign that the infant's stomach is not very mature, leading to excessive stomach acid, but this is not significantly related to the ventricular septal defect.