Exanthem subitum in infants is caused by human herpesvirus type 6 or type 7 infection; it is an acute febrile rash disease. During the acute phase, a sudden high fever may occur, with body temperatures reaching up to 39°C or even over 40°C, followed by the appearance of a rash after the fever subsides. Therefore, it is crucial to monitor body temperature closely. During periods of high fever in infants, timely antipyretic treatment should be administered, such as oral fever-reducing medications, combined with physical cooling methods. Additionally, it is important to monitor the infant's mental response and ensure they drink plenty of water. When the rash appears, maintaining skin cleanliness and hygiene to prevent skin infections and other measures should be taken. (Specific medication use should be conducted under the guidance of a doctor.)