How is bladder cancer diagnosed?

Written by Guan Hai Fang
Urology
Updated on September 23, 2024
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Firstly, imaging examinations such as ultrasound can be conducted, which if reveal tumors larger than 0.5 cm can serve as an initial screening for patients; IVU (Intravenous Urography) can show larger tumors as filling defects. Cystoscopy can also be performed by inserting a cystoscope to directly examine the bladder's shape, size, etc. If it appears round, with clear boundaries and without erosion, it is generally benign; if it has a cauliflower-like or seaweed-like appearance, it is generally malignant bladder cancer. Urine tests can also be conducted; cells from tumors found in fresh urine can lead to cytological examination of urine as an initial screening. Additionally, if conditions permit, a physical examination including a bimanual examination of the bladder can be done to preliminarily assess the tumor's size, the extent of invasion, depth, and its relationship with the pelvic wall.

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Written by Liu Liang
Oncology
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How is bladder cancer caused?

The causes of bladder cancer are not very clear so far, and they are related to factors such as environment, genetics, and lifestyle habits. However, two major risk factors are quite clear: one is smoking, and the other is long-term exposure to aromatic amines, which are occupational factors that are significant risks for causing bladder cancer.

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Written by Chen Feng
Urology
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Can urine odor be a sign of bladder cancer?

Urine with an unusual odor may be caused by bladder cancer, but the presence of an odor alone cannot be used to diagnose bladder cancer. Clinically, urine with an odor is commonly associated with urinary tract infections, as patients with such infections tend to have a higher amount of inflammatory secretions in their urine. Additionally, patients with urinary tract infections may lose some body water through sweating, leading to more concentrated urine, which can increase the odor. Bladder cancer patients are more susceptible to urinary tract infections, so they may also experience odorous urine. Clinically, bladder cancer is diagnosed through a combination of the patient's symptoms and supportive diagnostic tests. In the early stages of the disease, bladder cancer typically presents as painless hematuria (blood in the urine) that persists for an extended period. A routine urinalysis can be performed to check for elevated red blood cells in the urine. If bladder cancer is suspected, a cystoscopy can be conducted to identify any masses in the bladder and take biopsy samples for pathological examination. The presence of tumor cells in these samples generally confirms a diagnosis of bladder cancer.

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Written by Liu Liang
Oncology
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Is the bladder cancer embryonic antigen high?

Carcinoembryonic antigen (CEA) is significantly elevated, mainly seen in gastrointestinal tumors, especially in colorectal cancers such as colon and rectal cancers, where CEA elevation is more pronounced. It can also be notably higher in patients with lung adenocarcinoma, and bladder cancer might show an increase in CEA as well. However, the increase in CEA is not necessarily consistent, and its diagnostic value for bladder cancer is limited due to low specificity and sensitivity, making it not very instructive. The definitive diagnosis of bladder cancer primarily involves cystoscopy and taking a biopsy to confirm the presence of cancer.

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Written by Hu Zhong Dong
Medical Oncology
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Can early-stage bladder cancer be cured?

Bladder cancer is a relatively common malignant tumor in the urinary system and tends to occur more frequently in males, with the incidence rate being three to four times higher than that in females. Painless hematuria is likely to be caused by bladder cancer. Therefore, it is crucial to be cautious when hematuria occurs and to seek medical examination at a hospital as soon as possible, such as urinalysis and bladder ultrasound exams, which are non-invasive and relatively inexpensive. Early-stage bladder cancer can potentially be cured, especially if it is superficial. However, patients with poorly differentiated and highly malignant forms may undergo infusion chemotherapy and immunotherapy. Studies have shown that patients with minor bladder cancer, after undergoing systematic treatment, have a relatively high five-year survival rate.

doctor image
home-news-image
Written by Guan Hai Fang
Urology
1min 6sec home-news-image

How is bladder cancer diagnosed?

Firstly, imaging examinations such as ultrasound can be conducted, which if reveal tumors larger than 0.5 cm can serve as an initial screening for patients; IVU (Intravenous Urography) can show larger tumors as filling defects. Cystoscopy can also be performed by inserting a cystoscope to directly examine the bladder's shape, size, etc. If it appears round, with clear boundaries and without erosion, it is generally benign; if it has a cauliflower-like or seaweed-like appearance, it is generally malignant bladder cancer. Urine tests can also be conducted; cells from tumors found in fresh urine can lead to cytological examination of urine as an initial screening. Additionally, if conditions permit, a physical examination including a bimanual examination of the bladder can be done to preliminarily assess the tumor's size, the extent of invasion, depth, and its relationship with the pelvic wall.