What medicine is infused into the bladder for bladder cancer?

Written by Liu Liang
Oncology
Updated on September 10, 2024
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Postoperative intravesical chemotherapy infusion is very common in the treatment of bladder cancer. Common drugs used for infusion chemotherapy include mitomycin and anthracyclines such as epirubicin or pirarubicin. Gemcitabine is also frequently used for this purpose. The related side effects generally include irritation symptoms of the bladder, although some patients may experience relatively mild side effects.

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Written by Liu Liang
Oncology
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Does bladder cancer require the removal of the bladder?

Whether or not to remove the entire bladder in cases of bladder cancer depends on whether the tumor has invaded the base layer and whether there is distant metastasis. For non-muscle invasive bladder cancer, where the muscle layer is not invaded and there is no distant metastasis, typically found in stage 0 and stage 1 bladder cancer patients, there is no need for complete removal of the bladder. The standard treatment in such cases generally involves transurethral resection of the bladder tumor. If the tumor has invaded the base layer but there is no distant metastasis, termed muscle-invasive bladder cancer, patients in this category require radical cystectomy, which involves the removal of the entire bladder. If there is distant metastasis, termed metastatic bladder cancer, surgical treatment is not pursued; instead, palliative chemotherapy is the primary approach.

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Written by Guan Hai Fang
Urology
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How is bladder cancer diagnosed?

Firstly, imaging examinations such as ultrasound can be conducted, which if reveal tumors larger than 0.5 cm can serve as an initial screening for patients; IVU (Intravenous Urography) can show larger tumors as filling defects. Cystoscopy can also be performed by inserting a cystoscope to directly examine the bladder's shape, size, etc. If it appears round, with clear boundaries and without erosion, it is generally benign; if it has a cauliflower-like or seaweed-like appearance, it is generally malignant bladder cancer. Urine tests can also be conducted; cells from tumors found in fresh urine can lead to cytological examination of urine as an initial screening. Additionally, if conditions permit, a physical examination including a bimanual examination of the bladder can be done to preliminarily assess the tumor's size, the extent of invasion, depth, and its relationship with the pelvic wall.

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Written by Xu Chun Hua
Urology
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Early symptoms of bladder cancer

Hematuria is the most common and earliest symptom of bladder cancer, with 85% of patients experiencing intermittent gross hematuria which can decrease or stop on its own, often giving patients a false impression of improvement or cure, thus delaying treatment. Sometimes, hematuria is also found under a microscope, and the amount of bleeding is not necessarily consistent with the size, number, or malignancy of the tumor. The hematuria from bladder tumors can initially be mild, and other symptoms such as frequent urination, urgency, and painful urination may also occur; these are all manifestations of bladder tumors.

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Written by Liu Liang
Oncology
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What medicine is infused into the bladder for bladder cancer?

Postoperative intravesical chemotherapy infusion is very common in the treatment of bladder cancer. Common drugs used for infusion chemotherapy include mitomycin and anthracyclines such as epirubicin or pirarubicin. Gemcitabine is also frequently used for this purpose. The related side effects generally include irritation symptoms of the bladder, although some patients may experience relatively mild side effects.

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Written by Guan Hai Fang
Urology
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Is bladder cancer contagious?

Bladder cancer is not contagious, so there is no need to worry about that. Bladder cancer occurs when there is a cancerous transformation of bladder tissue, leading to the formation of bladder tumors. If the tumors are malignant, they are generally termed bladder cancer. Causes of bladder cancer can include long-term exposure to certain carcinogens, such as occupations involving dyes, leather, or paintwork. Another carcinogenic factor is smoking, which is related to about one-third of bladder cancer cases. Chronic infection or prolonged irritation by foreign bodies can also increase the risk of bladder cancer, as seen in cases with bladder stones, bladder diverticula, or chronic cystitis.