It has been three months since the last menstrual period, and if pregnancy has been definitively ruled out, then there must be a serious endocrine issue. It is necessary to identify the cause before treatment can be administered. Not all cases of amenorrhea are treated with the same medication.

First, an ultrasound examination should be performed to assess the condition of the pelvic cavity and the uterine cavity, including the thickness of the endometrium and the volume of the uterus. Then, after inducing menstruation or if the endometrium is particularly thin, a blood test should be performed to check levels of thyroid hormones, sex hormones, etc. If there is an issue with weight gain, tests for insulin and blood sugar levels should also be conducted, and medication should be chosen based on the results of these tests.