The Harm of Amenorrhea

Written by Li Shun Hua
Obstetrics and Gynecology
Updated on May 21, 2025
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In women, if amenorrhea occurs prematurely, it might indicate premature ovarian failure, which significantly impacts female reproductive function. This is because estrogen and progesterone, which are unique sex hormones in females, when depleted, can lead to atrophy of the reproductive organs, decreased libido, osteoporosis, and even early onset of heart disease. Therefore, hormone replacement therapy (HRT) can be applied in cases of premature ovarian failure. If amenorrhea occurs after the age of 40, it is considered normal and is a common phenomenon that every woman experiences. If there are no contraindications to medication, HRT can also be used, which can significantly slow down the aging process in women, improve their quality of life, and visibly enhance their well-being.

Other Voices

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Written by Shen Li Wen
Obstetrics and Gynecology
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Can you get pregnant with menstrual disorder and amenorrhea?

When women experience menstrual disorders such as amenorrhea, most of them are unable to conceive. This is because the ovarian secretion of hormones is abnormal during this period, and there is an ovulation obstacle, usually resulting in the absence of eggs. Thus, sexual intercourse during this time generally does not lead to conception. However, a very small number of women may experience occasional ovulation during amenorrhea. If they have normal sexual relations without contraception during this time, conception could still occur. Nonetheless, many women have abnormal hormone levels during amenorrhea, so even if pregnancy occurs, the abnormal hormone levels in early pregnancy could lead to complications such as missed abortion and miscarriage. It is recommended that women who want to conceive should first undergo regular treatment to restore normal menstrual cycles and resume ovulation before actively trying to conceive.

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Written by Zhang Xiu Rong
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Is amenorrhea a disease?

Amenorrhea is first divided into physiological or pathological. If it is physiological, it generally is not a major issue, but pathological cases must be treated symptomatically. For physiological amenorrhea, such as not menstruating for three months during the breastfeeding period, this is normal. It's mainly influenced by the secretion of prolactin from the ovaries, so it’s possible not to have menstruation during breastfeeding, and this is not a problem. Moreover, some people use medications, such as those used to treat endometriosis, which can cause amenorrhea; this type of amenorrhea is normal, and menstruation usually resumes after stopping the medication. Then there is pathological amenorrhea, typically seen with severe conditions like uterine endometrium or intrauterine adhesions, which can also cause a lack of menstruation. Additionally, ovarian secretory dysfunction, certain endocrine disorders, or premature ovarian failure, can all lead to amenorrhea, requiring related medical examinations and symptomatic treatment in a hospital.

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Written by Zhao Xiao Dong
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Is it normal to have amenorrhea without vaginal discharge?

The absence of vaginal discharge during amenorrhea is generally a normal phenomenon, indicating that the amenorrhea is caused by a reduction in estrogen and diminished ovarian function. This condition is commonly seen in endocrine disorders such as hyperprolactinemia or premature ovarian failure. It is necessary to examine the six female sex hormones and thyroid function to confirm the diagnosis. If the examination reveals elevated prolactin levels, diagnosing hyperprolactinemia, a head CT scan is generally required. If a pituitary tumor is present, surgical treatment should be conducted. If no pituitary tumor is found, treatment with a specific medication like bromocriptine is given, after which menstruation and normal vaginal discharge will resume. Another scenario is seen in cases of premature ovarian failure, which also leads to amenorrhea and a reduction in vaginal discharge. For premature ovarian failure, a common approach is to use cyclical hormone replacement therapy to restore menstruation and vaginal discharge.

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Written by Hou Jie
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How to induce menstruation after six months of amenorrhea?

If women are in the perimenopausal period and experience amenorrhea, it is not advised to use medication to induce menstruation. Artificially prolonging menstruation can sometimes lead to breast diseases, so excessive intervention is not recommended. This is a natural law of nature that we need to follow. For women who are not in menopause but experience amenorrhea, it is necessary to perform ultrasound and test six sex hormones. Sometimes, it may also be necessary to examine the pituitary gland to identify the specific cause of amenorrhea. Based on the specific cause, systematic treatment to regulate menstruation is required, and sometimes medication is necessary. If there is a pituitary tumor, surgical treatment might also be needed. (The use of medication should be conducted under the guidance of a professional doctor.)

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How to quickly induce menstruation when it has stopped.

Women with amenorrhea should first undergo a blood and urine HCG test to rule out the possibility of pregnancy. After excluding pregnancy, it is generally necessary to check the female sex hormone levels and thyroid function. Sometimes, specific diseases such as polycystic ovary syndrome, hyperprolactinemia, and premature ovarian failure can cause amenorrhea, and these specific diseases should be treated accordingly to induce menstruation. For polycystic ovary syndrome, treatment often involves the use of oral contraceptives to induce menstruation; for hyperprolactinemia, treatment typically involves the use of bromocriptine; for premature ovarian failure, estrogen-progestogen cycle replacement is usually prescribed. (Please use medications under the guidance of a doctor.)