What are the symptoms of cerebral atrophy?

Written by Zhang Hui
Neurology
Updated on September 13, 2024
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Some patients with brain atrophy may not exhibit any specific clinical symptoms and are only found to have brain atrophy through imaging studies, such as magnetic resonance imaging (MRI) of the brain. Some patients do exhibit clinical symptoms, and the common symptoms of brain atrophy mainly include the following manifestations. First, patients may experience a decline in memory function, such as frequently forgetting things they have just done, forgetting where they placed their wallet, or forgetting to bring keys when going out. Second, there may also be a decline in executive functions, such as difficulties in dressing or brushing teeth by oneself. Third, there may be a decline in computational abilities, to the extent that the patient cannot perform simple arithmetic. Additionally, brain atrophy may also present some psychiatric symptoms, such as hallucinations and incoherent speech.

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Written by Zhang Hui
Neurology
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Symptoms of cerebral atrophy

Mild cerebral atrophy may not present any clinical symptoms, and many elderly people show some degree of cerebral atrophy during imaging examinations, which should not be overly worrying. If the cerebral atrophy is more pronounced, it mainly manifests as cognitive dysfunction, such as a decline in memory, reduced computational abilities, diminished executive functions, and possibly the inability to perform complex movements, such as being unable to brush one's teeth or dress oneself. In severe cases, individuals may experience personality changes, becoming irritable, easily angered, suspicious, and may even exhibit psychiatric symptoms, primarily hallucinations.

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Written by Zhang Hui
Neurology
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The reason why people with cerebral atrophy curse

This situation primarily arises from brain atrophy causing Alzheimer's disease, which is a very common neurodegenerative disorder. In the middle and late stages, patients may exhibit significant personality changes, becoming irritable, easily angered, and paranoid, often engaging in behaviors such as hitting or cursing others. They may also experience hallucinations, such as vivid visual and auditory hallucinations. The disease is mainly due to the degeneration and death of neurons in the temporal lobe and hippocampus, leading to the atrophy of the cerebral cortex. This causes the release of some of the patient's primitive instincts, leading to a series of clinical manifestations, which can be symptomatically managed.

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Written by Li Jiao Yan
Neonatology
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Symptoms of baby brain atrophy

The symptoms of baby brain atrophy include the following: First, the child shows no interest in the surroundings, poor responsiveness, significantly reduced movements, poor sucking ability, and often chokes on milk. Second, the child with brain atrophy exhibits abnormal muscle tone and posture. Symptoms of cerebellar atrophy include difficulty in abducting the thighs, difficulty in extending the knees, legs straightened and adducted when held upright, legs crossed in a scissor-like manner, bent elbow and wrist joints, and the hands often clenched with the thumb turned inward. Third, congenital reflexes are weakened or may not appear at all, such as the rooting reflex, grasp reflex, and embrace reflex, which are either weakened or completely absent. Fourth, there is limited voluntary movement; the baby cannot reach out voluntarily to grab liked objects after five months or always uses one hand to reach for things. Fifth, there are signs of intellectual disability, delayed language development, or language disorders.

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Written by Zhang Hui
Neurology
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Can cerebellar atrophy be treated?

Cerebellar atrophy is a finding observed in imaging studies, often discovered during imaging exams without necessarily presenting corresponding clinical symptoms. The possibility of treating cerebellar atrophy depends primarily on its underlying cause. For instance, cerebellar atrophy caused by genetic disorders, such as spinocerebellar ataxia, which results from genetic mutations, lacks highly effective treatment options. The primary approach in such cases is symptomatic treatment, including administering medications that nourish the nerves. Generally, these diseases progressively worsen. Cerebellar atrophy can also be due to neurodegenerative diseases like multiple system atrophy, which are untreatable. However, cerebellar atrophy caused by long-term alcohol consumption may improve to some extent with abstinence and high doses of vitamin B complex. Additionally, cerebellar atrophy resulting from chronic significant ischemia can be alleviated by addressing the ischemic conditions.

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Written by Zhang Hui
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MRI manifestations of brain atrophy

Patients with cerebral atrophy display clear signs on cranial Magnetic Resonance Imaging (MRI). The manifestations on MRI primarily include notably widened cerebral sulci, obvious atrophy of the cerebral lobes, and enlarged ventricles, which are typical presentations of cerebral atrophy. Cerebral atrophy can be categorized into atrophy of the cerebrum, cerebellum, and brainstem, each showing different characteristics on MRI, which requires careful differentiation. There are many causes of cerebral atrophy, such as degenerative diseases like Alzheimer's disease, which leads to cerebral atrophy. Cerebral thrombosis and poor cerebral vascular conditions can also cause cerebral atrophy due to insufficient blood supply to the brain. Additionally, drug toxicity and chronic alcoholism can lead to cerebral atrophy, which also needs to be differentiated carefully.