How is tuberculosis contracted?

Written by Wang Xiang Yu
Pulmonology
Updated on July 03, 2025
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Tuberculosis (TB) is an infectious disease and currently classified as a Class B infectious disease for management purposes. As an infectious disease, TB has a specific causative agent, the Mycobacterium tuberculosis complex, which includes four types: human, bovine, African, and rodent. Over 90% of human tuberculosis infections are caused by the human type of Mycobacterium tuberculosis, with the remainder caused by either bovine or African types. To contract tuberculosis, one must be exposed to an infectious source, primarily those with secondary tuberculosis. Tuberculosis patients can release the bacteria into the air through coughing, sneezing, laughing, or speaking loudly. Healthy individuals or the general population may then inhale these bacteria during breathing, leading to infection of the lungs and the development of tuberculosis.

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How is tuberculosis diagnosed?

The diagnosis of tuberculosis primarily involves combining relevant clinical symptoms, such as whether there is cough, expectoration, low fever, night sweats, and blood in phlegm. It also requires considering the patient's chest imaging features, whether there is obvious infection, fresh exudation, cavities, as well as sputum tests. For example, if the sputum stain for acid-fast bacilli is positive, and the sputum culture is positive, using these comprehensive diagnostic methods, tuberculosis can be diagnosed, after which anti-tuberculosis treatment should be initiated.

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Written by Wang Xiang Yu
Pulmonology
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Can tuberculosis relapse?

Tuberculosis can relapse, and the answer is definitely yes. In clinical practice, we see many patients who have had tuberculosis and, years later, experience a recurrence of the disease, even multiple recurrences. However, the probability of this is generally not high. As long as everyone follows the doctor's instructions for standard anti-tuberculosis treatment and completes the full course of treatment, most patients can be cured. However, there are a few people whose treatment process is not standard, or who stop taking their medication on their own, and these actions can increase the risk of tuberculosis recurrence.

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Written by Wang Xiang Yu
Pulmonology
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Does tuberculosis cause fever?

Does tuberculosis cause fever? Certainly, fever can occur. Fever is one of the most common clinical manifestations of tuberculosis, which can be mild or high fever. Most cases of tuberculosis mainly present as afternoon febrile flushes, or say, an evening low-grade fever. In a few cases, such as infectious pneumonia or more severe infections like tuberculous pleurisy, there can be high fever, and these fever episodes may last a long time and be recurrent, making them difficult to control.

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Written by Wang Xiang Yu
Pulmonology
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Can tuberculosis be fatal?

Can tuberculosis be fatal? Of course, the answer is yes. Many diseases can lead to death, even a common cold can potentially result in death, let alone tuberculosis, which is an extraordinary illness. Currently, the mortality rate for tuberculosis patients is relatively low because the treatment for tuberculosis has improved significantly compared to the past. However, there are still a small number of patients who, due to untimely treatment of tuberculosis, discontinuation of medications on their own accord or non-compliance with medical advice, or who have other serious underlying diseases, may not tolerate the tuberculosis treatment. As a result, they could potentially die from adverse reactions to the tuberculosis medications.

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Written by Wang Xiang Yu
Pulmonology
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Symptoms of tuberculosis

Tuberculosis of the lung presents in many forms, as there are also various types of pulmonary tuberculosis, each exhibiting different symptoms. However, the most common symptoms primarily include coughing and expectoration, which are the most typical manifestations of pulmonary tuberculosis. The cough in pulmonary tuberculosis is generally mild, either dry or producing only a small amount of phlegm. If the tuberculosis is accompanied by cavities, the amount of phlegm may be larger. If there is a bacterial infection in addition to the tuberculosis, the phlegm may become purulent. Some patients with pulmonary tuberculosis may also experience hemoptysis, which can vary in amount from light to severe. A small number of patients may suffer from chest pain and difficulty breathing. Additionally, there are systemic symptoms associated with pulmonary tuberculosis, such as fever (both low and high fever may occur), night sweats, and fatigue, among others.