Aplastic anemia is caused by how?

Written by Li Fang Fang
Hematology
Updated on December 11, 2024
00:00
00:00

Aplastic anemia currently still has an uncertain etiology. However, clinical observations have suggested that chemotherapy drugs, viral infections, and radiation exposure might be related to the occurrence and development of aplastic anemia. Regardless of the cause, these factors all involve abnormalities in immune function. Abnormal immune function leads to the occurrence and development of aplastic anemia. Therefore, immunosuppressive therapy is often effective for patients with aplastic anemia in clinical settings. (Medication use should be conducted under the guidance of a professional doctor.)

Other Voices

doctor image
home-news-image
Written by Li Fang Fang
Hematology
41sec home-news-image

What medicine is used for aplastic anemia?

The main drugs used for aplastic anemia are immunosuppressants and cyclosporine. In addition to cyclosporine, low doses of hormones, androgens, and traditional Chinese medicine can also be used to stimulate bone marrow hematopoiesis. If the medication is effective, continue with oral administration; if ineffective, further consideration of bone marrow transplantation is needed. During the treatment process, it is necessary to regularly review the routine blood tests and, if necessary, provide support treatment with red blood cell and platelet transfusions.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
46sec home-news-image

Is aplastic anemia contagious?

Aplastic anemia is a bone marrow failure disease and is not infectious; it cannot be transmitted. Aplastic anemia is considered a hematological disorder and should be routinely diagnosed and treated in the department of hematology. It falls under the category of bone marrow failure diseases, and its main clinical manifestations are infection, anemia, and bleeding, with a complete blood count showing a decrease in all blood cells. Patients with aplastic anemia can be divided into acute aplastic anemia and chronic aplastic anemia, and there are some differences in the treatment of the two.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
44sec home-news-image

What medicine is used for aplastic anemia?

Aplastic anemia, whether acute or chronic, primarily uses immunosuppressive agents and hematopoietic stimulants for treatment. Cyclosporine is commonly used clinically among immunosuppressants, while the medicines stimulating bone marrow hematopoiesis mainly include androgens such as danazol and stanozolol. These medications all have associated adverse reactions: immunosuppressants can lead to hypertension, hyperglycemia, impaired liver and kidney function, and gum hypertrophy, while the main adverse reactions of hematopoietic androgens are liver damage. (Please use medications under the guidance of a doctor.)

doctor image
home-news-image
Written by Li Fang Fang
Hematology
1min 3sec home-news-image

What are the symptoms of aplastic anemia?

The symptoms of aplastic anemia include three main symptoms: firstly, infections; secondly, anemia; and thirdly, bleeding. Infections occur due to a decrease in white blood cells, especially neutrophils, resulting in poor resistance in patients making them susceptible to subsequent infections, including infections of the lungs, digestive system, urinary system, and skin and mucous membranes. Anemia occurs due to a reduction in red blood cells, causing symptoms such as dizziness, headaches, fatigue, reduced tolerance to physical activity, and poor appetite. A reduction in platelets significantly increases the risk of bleeding, especially when platelets are less than 20 times 10 to the ninth power per liter, which can lead to bleeding in the skin, mucous membranes, organs, and even cerebral hemorrhage.

doctor image
home-news-image
Written by Li Fang Fang
Hematology
50sec home-news-image

Aplastic anemia is classified into several types.

Aplastic anemia is divided into two types: acute aplastic anemia and chronic aplastic anemia. Acute aplastic anemia presents suddenly and is severe. Treatment requires intensified immunotherapy or suppression of hematopoietic stem cell transplantation. Chronic aplastic anemia develops slowly, has a longer history, and is relatively less severe. The treatment for chronic aplastic anemia mainly involves immunotherapy combined with therapy to promote hematopoiesis. In addition, regardless of the type, all cases of aplastic anemia require regular complete blood count checks and, when necessary, supportive treatment with red blood cell and platelet transfusions.