How long can one live with aplastic anemia?

Written by Li Fang Fang
Hematology
Updated on September 19, 2024
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The lifespan of patients with aplastic anemia depends on the type and the effectiveness of the treatment. Aplastic anemia is classified into acute aplastic anemia and chronic aplastic anemia. In cases of acute aplastic anemia, cure is possible through intensified immunotherapy or hematopoietic stem cell transplantation; however, without aggressive treatment, the survival period is relatively short, generally not exceeding one year. Chronic aplastic anemia, on the other hand, has a longer medical history, and patients can often live for ten to twenty years or more. However, throughout this period, ongoing transfusions of red blood cells and platelets are required to support treatment.

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Written by Li Fang Fang
Hematology
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The main cause of aplastic anemia is.

The causes of aplastic anemia are considered to be of three types: abnormalities in hematopoietic stem cells, abnormalities in the bone marrow microenvironment, and abnormalities in immune factors. Among these, abnormalities in immune factors play a dominant role. Therefore, most patients with aplastic anemia see some improvement after receiving immunosuppressive therapy clinically. However, there is a small subset of patients with aplastic anemia for whom immunosuppressive therapy is not effective, and the causes of the disease in these patients are not well understood and may be congenital, such as congenital dyskeratosis.

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Written by Li Fang Fang
Hematology
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How long can one live with aplastic anemia?

The lifespan of patients with aplastic anemia depends on the type and the effectiveness of the treatment. Aplastic anemia is classified into acute aplastic anemia and chronic aplastic anemia. In cases of acute aplastic anemia, cure is possible through intensified immunotherapy or hematopoietic stem cell transplantation; however, without aggressive treatment, the survival period is relatively short, generally not exceeding one year. Chronic aplastic anemia, on the other hand, has a longer medical history, and patients can often live for ten to twenty years or more. However, throughout this period, ongoing transfusions of red blood cells and platelets are required to support treatment.

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Written by Li Fang Fang
Hematology
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Is aplastic anemia leukemia?

Aplastic anemia is not leukemia, but there is a very small chance that aplastic anemia can transform into leukemia. Aplastic anemia is a bone marrow failure syndrome, and its clinical presentation often includes pancytopenia. It can be classified into acute aplastic anemia and chronic aplastic anemia. Leukemia often manifests with high white blood cell counts, anemia, and low platelet counts. It is caused by the infiltration of leukemia cells into the bone marrow, leading to the suppression of normal hematopoiesis, and is classified as a malignant hematological tumor. Leukemia can be divided into acute leukemia and chronic leukemia.

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Written by Li Fang Fang
Hematology
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What to eat for aplastic anemia

Patients with aplastic anemia should eat light, easily digestible foods, and soft diet, avoiding too hard foods, and foods with spines or bones to prevent these foods from scratching the mucous membrane of the digestive tract and causing gastrointestinal bleeding. Additionally, patients with aplastic anemia must also take medications to control the progression of the disease, the related medications mainly include immunosuppressants, such as cyclosporine, as well as hematopoietic stimulants and traditional Chinese medicine formulations. Hematopoietic drugs include androgens, such as danazol and stanozolol, etc., and traditional Chinese medicines include compound alumite pills, rejuvenating blood tablets, etc. (Please use specific medications under the guidance of a doctor, and do not self-medicate.)

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Written by Li Fang Fang
Hematology
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The etiology of aplastic anemia

The etiology of aplastic anemia currently has no absolute cause, but the more supported theories concerning its etiology include the soil, pest, and seed theories. The soil theory refers to abnormalities in the microenvironment within the bone marrow, which causes an abnormal growth environment for hematopoietic stem cells, consequently limiting their growth. The seed theory indicates a decrease in the number and quality of hematopoietic stem cells in the bone marrow, leading to bone marrow regeneration failure. The pest theory refers to immunological factors, which play a significant role in aplastic anemia, suggesting a disorder in the patient's immune function that leads to bone marrow regeneration failure.