Is aplastic anemia leukemia?

Written by Li Fang Fang
Hematology
Updated on September 28, 2024
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Aplastic anemia is not leukemia, but there is a very small chance that aplastic anemia can transform into leukemia. Aplastic anemia is a bone marrow failure syndrome, and its clinical presentation often includes pancytopenia. It can be classified into acute aplastic anemia and chronic aplastic anemia. Leukemia often manifests with high white blood cell counts, anemia, and low platelet counts. It is caused by the infiltration of leukemia cells into the bone marrow, leading to the suppression of normal hematopoiesis, and is classified as a malignant hematological tumor. Leukemia can be divided into acute leukemia and chronic leukemia.

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Written by Li Fang Fang
Hematology
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Is aplastic anemia contagious?

Aplastic anemia is not contagious and has a minor hereditary factor, meaning that if a family member has aplastic anemia, it is generally not inherited by the next generation. The cause of aplastic anemia is still unclear, but possible reasons include: 1. Damage to hematopoietic stem cells. After the hematopoietic stem cells are damaged, it leads to limited stem cell proliferation and reduced hematopoiesis. 2. Damage to the hematopoietic microenvironment. Damage to the hematopoietic microenvironment can lead to changes that disrupt the regeneration of hematopoietic stem cells. 3. Immune factors. Immune factors can cause immune damage, directly damaging hematopoietic stem cells, thereby causing bone marrow regeneration disorders.

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Written by Zhang Xiao Le
Hematology
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Is it good to transfuse platelets for aplastic anemia with low platelets?

Aplastic anemia is a type of bone marrow failure syndrome, with patients often experiencing a decrease in all blood cells in the peripheral blood. As a result, patients typically face a higher risk of infections and bleeding. Treatment for aplastic anemia is a long-term process, and hematopoiesis often cannot be restored quickly. Therefore, especially in severe cases of aplastic anemia, patients' blood cells remain at relatively low levels for an extended period, placing them at severe risk of infections and bleeding. If platelets fall below 20*10^9/L, it is necessary to administer platelet transfusions to prevent severe bleeding.

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Written by Li Fang Fang
Hematology
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What medicine is used for aplastic anemia?

Aplastic anemia, whether acute or chronic, primarily uses immunosuppressive agents and hematopoietic stimulants for treatment. Cyclosporine is commonly used clinically among immunosuppressants, while the medicines stimulating bone marrow hematopoiesis mainly include androgens such as danazol and stanozolol. These medications all have associated adverse reactions: immunosuppressants can lead to hypertension, hyperglycemia, impaired liver and kidney function, and gum hypertrophy, while the main adverse reactions of hematopoietic androgens are liver damage. (Please use medications under the guidance of a doctor.)

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Written by Zhang Xiao Le
Hematology
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The differences between aplastic anemia and megaloblastic anemia.

Aplastic anemia is a type of bone marrow failure syndrome where patients can present with reduced total blood cells in the peripheral blood, without enlargement of the liver, spleen, or lymph nodes, and an increased ratio of peripheral blood lymphocytes. Bone marrow indicates low regeneration, reduced hematopoietic tissue, and increased non-hematopoietic tissue, with the condition arising from changes in the bone marrow microenvironment leading to a reduction in blood cells. Megaloblastic anemia, also known as nutritional anemia, is primarily caused by a lack of folate and vitamin B12, leading to a red blood cell synthesis disorder and resulting in anemia. Severe megaloblastic anemia can also present with reduced total blood cells. However, the red blood cells typically exhibit macrocytic anemia. In contrast, aplastic anemia generally presents with normocytic anemia.

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Written by Li Fang Fang
Hematology
46sec home-news-image

Is aplastic anemia leukemia?

Aplastic anemia is not leukemia, but there is a very small chance that aplastic anemia can transform into leukemia. Aplastic anemia is a bone marrow failure syndrome, and its clinical presentation often includes pancytopenia. It can be classified into acute aplastic anemia and chronic aplastic anemia. Leukemia often manifests with high white blood cell counts, anemia, and low platelet counts. It is caused by the infiltration of leukemia cells into the bone marrow, leading to the suppression of normal hematopoiesis, and is classified as a malignant hematological tumor. Leukemia can be divided into acute leukemia and chronic leukemia.