Can Parkinson's disease be cured?

Written by Zhang Hui
Neurology
Updated on May 22, 2025
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Parkinson's disease is a movement disorder, and there are many medications and treatments that can improve the quality of life for patients and alleviate their clinical symptoms. However, from the current medical perspective, it is impossible to achieve a complete cure. Therefore, patients with Parkinson's disease must not be deceived and should seek treatment at accredited hospitals. Currently, treatment for this disease primarily involves pharmacotherapy. There are various medications available, commonly including dopamine receptor agonists, Levodopa-based drugs, as well as some amantadine and anticholinergic drugs. Each drug has its own characteristics and should be chosen based on the patient's condition. Additionally, some patients in the middle or later stages may also undergo deep brain stimulation surgery to improve symptoms. (Please use medication under the guidance of a professional physician and do not medicate blindly.)

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Written by Zhang Hui
Neurology
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How to medicate for the rigidity in Parkinson's disease?

Parkinson's disease presents with rigidity, mainly due to increased muscle tone and muscle rigidity, which is a very important clinical manifestation of Parkinson's disease. The medications used for rigidity in Parkinson's disease mainly include the following types. The first type is dopamine receptor agonists, which can improve limb muscle rigidity to some extent and delay the progression of the disease. The second type of medication is levodopa preparations, which are currently the gold standard for treating Parkinson's disease. Many patients experience significant clinical improvement after taking the medication. The third type of medication includes some anticholinergic drugs. These drugs are particularly effective against tremors and also have some effect in improving rigidity. Medication for Parkinson's disease must be taken under the guidance of a doctor. It is also important to note that levodopa preparations should be taken on an empty stomach or two hours after a meal for better efficacy.

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Written by Zhang Hui
Neurology
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How is Parkinson's disease diagnosed?

For the diagnosis of Parkinson's disease, the patient's medical history and symptoms are very important, and physical examinations are also an important reference for diagnosis. The physical examination generally involves checking the patient's muscle tone and looking for signs of bradykinesia. In terms of auxiliary examinations, on one hand, it is necessary to perform ceruloplasmin tests, which primarily aim to exclude hepatolenticular degeneration. Brain MRI scans are also conducted to exclude other causes of secondary Parkinson’s disease, such as normal pressure hydrocephalus and cerebrovascular diseases. Additionally, these patients need to undergo olfactory tests and some PET-CT scans to clarify the diagnosis.

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Written by Zhou Yan
Geriatrics
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Early symptoms of Parkinson's disease

Parkinson's disease begins inconspicuously and progresses gradually. There are two main categories of symptoms in Parkinson's disease: motor symptoms and non-motor symptoms. In the early stages of the disease, one can appear normal, or may experience motor symptoms like bradykinesia or rigidity, often starting asymmetrically. Symptoms commonly begin on one side of the upper limbs, and less frequently start from the lower limbs, eventually spreading to the limbs on the other side. Non-motor symptoms can occur at various stages of Parkinson's disease, including the pre-motor phase, such as loss of smell, sleep disturbances, constipation, depression, and more.

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Written by Zhang Hui
Neurology
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Is Parkinson's disease progressing quickly?

Parkinson's disease is a degenerative disease of the nervous system that has a very concealed onset and progresses very slowly, making the progression of this disease not rapid. Patients can generally take care of themselves for about three to five years, or even five to ten years, without having to worry too much about this disease. This disease primarily causes patients to experience obvious bradykinesia, mask-like faces, drooling, resting tremors, and increased muscle tone among other clinical manifestations, which can significantly distress patients. However, the progression of this disease is relatively slow, and the signs and symptoms on the left and right sides of the body are also asymmetric. After effective pharmacological treatments, such as commonly used levodopa and dopamine receptor agonists, patients' symptoms can usually be well controlled and the progression is slow. If the disease progresses very quickly, it could potentially be Parkinsonian syndrome.

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Written by Zhang Hui
Neurology
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Where to treat Parkinson's disease

Parkinson's disease is a very common neurodegenerative disease in neurology. Therefore, if Parkinson's disease is suspected, treatment can be sought in the neurology department, which is available in most hospitals. Many neurologists have extensive experience in treating Parkinson's disease. The treatment primarily includes medication and surgery. Medication therapy mainly refers to the administration of anticholinergic drugs or dopamine receptor agonists, as well as preparations of Levodopa. These medications can help improve symptoms, such as reducing muscle rigidity and tremors. Surgical treatment mainly refers to deep brain stimulation, which is suitable for patients who have been clearly diagnosed with Parkinson's disease for over five years and whose primary symptom is tremor, without significant dementia.