What are the symptoms of Parkinson's disease?

Written by Zhang Hui
Neurology
Updated on May 02, 2025
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Parkinson's disease is a relatively common neurological disorder and a degenerative disease of the nervous system, as well as an extrapyramidal disorder. The symptoms of Parkinson's disease primarily include the following: The first major category is motor symptoms. The motor symptoms of Parkinson's disease mainly include bradykinesia, where the patient is generally slow in all actions, such as slow walking, slow dressing, slow turning, etc. There are also symptoms of increased muscle tone and stiffness in the muscles, along with resting tremor of the limbs, unstable posture, and a tendency to fall. The second major category of symptoms is non-motor symptoms, which are also very important in Parkinson's disease. For instance, patients may experience significant sleep disturbances, a reduction in the sense of smell, dizziness, constipation, frequent urination, and other clinical manifestations.

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Written by Zhang Hui
Neurology
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Is Parkinson's disease hereditary?

A small portion of Parkinson's disease has a genetic predisposition. According to research statistics, about 5% to 10% of Parkinson’s disease cases are familial, caused by certain gene mutations leading to neurodegeneration. This part of the disease does have a genetic predisposition. However, it does not mean that if the parents have the disease, the child will definitely inherit it; environmental factors are also related. Most cases of Parkinson’s disease do not have a genetic predisposition and are sporadic, possibly related to cerebral ischemia, hypoxia, stress, mitochondrial dysfunction, and long-term exposure to certain toxins. These aspects are definitely not hereditary. Parkinson's disease is a neurodegenerative disorder that can cause symptoms such as bradykinesia, increased muscle tone, and unstable posture. It is important to seek medical treatment promptly.

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Written by Zhang Hui
Neurology
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What is needed to diagnose Parkinson's disease?

The definitive diagnosis of Parkinson's disease primarily relies on the patient's medical history, clinical manifestations, and a thorough physical examination by a neurologist. If the onset of the disease is very slow, presenting with symptoms such as bradykinesia and tremors, and the neurologist observes heightened muscle tone and slow movements during the examination, a high suspicion of this disease is warranted. Additionally, certain auxiliary tests are necessary, commonly including: First, testing the patient's sense of smell is crucial, as a reduced sense of smell is very important in diagnosing Parkinson's disease. Second, some brain MRI scans are needed mainly to exclude some secondary Parkinson's syndromes. Third, a brain PET-CT scan can be performed to examine the functionality of the striatum. Furthermore, an ultrasound of the substantia nigra in the midbrain can also be conducted, which holds significant value in assisting the diagnosis.

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Written by Zhang Hui
Neurology
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Is tremor Parkinson's disease?

Tremor and Parkinson's disease are two completely different concepts. Tremor is not necessarily Parkinson's disease, and Parkinson's disease does not necessarily involve tremor. Tremor is just a clinical symptom that can appear in many diseases. In addition to Parkinson's disease, there are also some essential tremors which are genetic. Patients usually experience tremors in their hands when maintaining certain postures, and may also have head tremors. This is a relatively benign disease with a generally good prognosis. Additionally, patients with hyperthyroidism may also experience limb tremors, but this is not Parkinson's disease. Moreover, many patients with Parkinson's disease experience bradykinesia and rigidity, and might not necessarily have limb tremors. Therefore, these two concepts are different; tremor is not necessarily Parkinson's disease.

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Written by Zhang Hui
Neurology
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What tests are done for Parkinson's disease?

Parkinson's disease is a degenerative disease of the nervous system. Many patients report that numerous examinations did not identify a clear cause of the disease, which is typical of this condition due to the lack of very effective diagnostic methods. Patients' symptoms gradually worsen, manifesting as motor slowness, limb tremors, muscle rigidity, and other clinical signs. There are also symptoms such as constipation and dizziness. Generally, the following examinations are recommended for Parkinson's disease: First, complete a cranial MRI scan. The primary purpose of a cranial MRI is to exclude other causes of Parkinson's-like symptoms, such as cerebral thrombosis, brain tumors, or inflammation. Second, perform olfactory tests, as some patients may experience a significant reduction in their sense of smell early on. Third, conduct induced sleep monitoring, since some patients may have prominent sleep disorders. Additionally, it is suggested to perform striatal dopaminergic transporter imaging, a type of DAT scan. Although this scan is quite expensive, it can clearly reflect the function of the striatum.

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Written by Zhang Hui
Neurology
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What to do about constipation in Parkinson's disease?

Among Parkinson's disease patients, constipation is a very common clinical symptom. In fact, many patients have experienced constipation for many years before the onset of Parkinson's disease symptoms, mainly due to the impact on some autonomic nerves in the intestines. For Parkinson's patients experiencing constipation, the main suggestions are: First, be sure to drink plenty of water. Drinking enough water can sufficiently lubricate the intestines and facilitate smoother bowel movements. Second, be sure to eat plenty of fresh vegetables and fruits. Vegetables and fruits are rich in vitamin C and can promote gastrointestinal motility. Additionally, it is recommended for patients to eat more bananas, as bananas have an evident laxative effect. Also, eat less of certain foods that can dry out the stool, such as sweet potatoes and chestnuts. If necessary, patients can be given laxative medications, and if bowel movements are extremely difficult, enemas can also be administered.