What tests are done for Parkinson's disease?

Written by Zhang Hui
Neurology
Updated on September 21, 2024
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Parkinson's disease is a degenerative disease of the nervous system. Many patients report that numerous examinations did not identify a clear cause of the disease, which is typical of this condition due to the lack of very effective diagnostic methods. Patients' symptoms gradually worsen, manifesting as motor slowness, limb tremors, muscle rigidity, and other clinical signs. There are also symptoms such as constipation and dizziness. Generally, the following examinations are recommended for Parkinson's disease: First, complete a cranial MRI scan. The primary purpose of a cranial MRI is to exclude other causes of Parkinson's-like symptoms, such as cerebral thrombosis, brain tumors, or inflammation. Second, perform olfactory tests, as some patients may experience a significant reduction in their sense of smell early on. Third, conduct induced sleep monitoring, since some patients may have prominent sleep disorders. Additionally, it is suggested to perform striatal dopaminergic transporter imaging, a type of DAT scan. Although this scan is quite expensive, it can clearly reflect the function of the striatum.

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Written by Zhang Hui
Neurology
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How is Parkinson's disease cured?

The treatment of Parkinson's disease involves various aspects, and the principle of its treatment is not to aim for complete effectiveness but for prolonged and sustainable management. It is important not to be tempted by temporary symptom improvement and miss out on a sequential treatment that could last for many years. The treatment of Parkinson’s disease mainly includes the following aspects: The first aspect is the care of daily life, which is very important. It is necessary to install some very convenient facilities at home for the patient, such as installing some handles, using some higher chairs, etc., all of which help to improve the quality of life for the patient. The second aspect is pharmacotherapy. According to the patient's condition, appropriate anti-Parkinson's medication is selected, mainly including dopamine receptor agonists, COMT inhibitors, and some levodopa preparations. Adjusting medication is very complex and must be conducted under the guidance of a professional neurologist. In addition, attention should also be paid to the treatment of non-motor symptoms, such as treating the patient's constipation, depression, etc.

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Written by Zhang Hui
Neurology
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What medicine is used for Parkinson's disease?

Parkinson's disease is a relatively common neurological disorder, with a higher incidence in middle-aged and elderly people. Currently, there is no specific cure for the disease, but there are many medications that can significantly improve the symptoms of Parkinson's disease. The commonly used medications mainly include: The first major category is Levodopa preparations. This type of medication has good efficacy but can cause some adverse drug reactions and may provoke the occurrence of motor complications. It should be taken under the advice of a doctor. The second major category of drugs is dopamine receptor agonists. These drugs also have relatively good effects and can improve the motor symptoms of patients, though they may be a bit expensive. Third, anticholinergic drugs. They can significantly improve the patients' normal symptoms, but should not be taken by patients with cognitive impairments. Additionally, there are monoamine oxidase inhibitors and COMT inhibitors that can also be used.

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Written by Zhang Hui
Neurology
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How does one get Parkinson's disease?

Parkinson's disease is a degenerative disease of the nervous system. The actual mechanism of the disease is not very clear, and its fundamental cause has not yet been identified. It is generally believed that Parkinson's disease is mainly caused by the following factors. First, genetic factors. Some cases of Parkinson's disease have a clear familial tendency, where patients may experience mutations in synaptic nuclear protein genes, leading to abnormal aggregation of these proteins. This abnormal aggregation can damage the neurons in the substantia nigra of the midbrain, leading to Parkinson's disease. Second, there are some external factors related to sporadic cases of Parkinson's. These may be closely related to oxidative stress, trauma, poisoning, or an excessive stress response of the body. However, the specific cause is not very clear. Parkinson's disease, which causes symptoms such as bradykinesia, tremors, and rigidity, requires active treatment to improve the quality of life of the patients.

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Written by Zhang Hui
Neurology
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What are the symptoms of Parkinson's disease?

Parkinson's disease is a relatively common disease among the elderly, causing significant inconveniences in their daily lives and making it difficult for them to move. Moreover, this disease progressively worsens. Overall, the symptoms of Parkinson's disease primarily include noticeable movement slowness; patients perform tasks very slowly, such as wrapping dumplings or rolling dumpling wrappers, which are done clumsily and slowly. They also dress, turn over in bed, and tie shoelaces very slowly. Additionally, there are evident symptoms such as resting tremors and muscle rigidity. Some people may experience a panicked gait, rushing forward and unable to control their steps. Patients might also experience severe constipation, a reduced sense of smell, and some have sensory abnormalities in their limbs.

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Written by Zhou Yan
Geriatrics
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What is the best way to exercise for Parkinson's disease?

Patients with Parkinson's disease should undergo comprehensive treatment and full management. Drug treatment is the core treatment plan, but it is also necessary to include physical rehabilitation and psychological therapy. For physical therapy, patients should be encouraged to exercise more, as this can help improve symptoms and slow the progression of the disease. The type and intensity of exercise should be chosen based on the patient's motor symptoms. Tai Chi, jogging, brisk walking, and aerobics are all suitable forms of exercise, and it is advisable to exercise four times a week, with each session lasting about 30 minutes. Evidence has shown that Tai Chi can improve patients' balance disorders, and long-term persistence in exercise can help improve their quality of life.