Can Parkinson's disease be cured?

Written by Zhang Hui
Neurology
Updated on September 11, 2024
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Parkinson's disease is a degenerative disease of the nervous system that currently cannot be cured in medicine. It is important to choose the right treatment plan to avoid being deceived. Parkinson's disease is mainly caused by the irreversible death of dopaminergic neurons in the substantia nigra, resulting in clinical manifestations such as bradykinesia, muscular rigidity, and tremors in limbs. Other non-motor symptoms include reduced sense of smell, constipation, anxiety, depression, and orthostatic hypotension. Treatment primarily focuses on symptomatic relief, and it is not expected to achieve complete remission. Commonly used medications include levodopa, anticholinergics, and activators of levodopa and dopamine receptors. Symptoms in patients usually progressively worsen, and curing the disease is very difficult.

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Written by Zhang Hui
Neurology
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Late-stage symptoms of Parkinson's disease

Parkinson's disease is a progressively worsening neurodegenerative disorder of the nervous system, initially manifesting as bradykinesia, resting tremor, and other symptoms. As the disease progresses, the symptoms become increasingly severe. In the later stages, symptoms may include significant postural and gait abnormalities, such as obvious stooping and difficulty starting to walk, a phenomenon known as freezing, and turning around can also be difficult. Additionally, in the late stages, swallowing dysfunction may occur, leading to clinical signs such as coughing while drinking water and articulation disorders. Furthermore, individuals with Parkinson's disease are particularly prone to falling in the later stages due to impaired balance functions.

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Neurology
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What is Parkinson's disease gait?

Patients with Parkinson's disease have a distinctive gait; typically, their torso leans forward, and their arms do not move much. When they walk, they exhibit a hurried gait with short, scurrying steps. That is, they take small steps that progressively get faster and faster, making stopping very difficult when they reach their destination. This is a typical scenario often referred to as a "scampering gait." Many experienced doctors can frame a preliminary diagnosis of Parkinson's disease just by observing the patient’s walk. Parkinson's disease also leads to unstable posture and gait, increasing the risk of falls and fractures. Therefore, it's important to take precautions at home by installing handrails to assist the patient in standing and walking, preventing accidental injuries.

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Written by Zhang Hui
Neurology
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Is Parkinson's disease scary?

Parkinson's disease is not a terrifying disease, as its onset is relatively hidden and slow, with gradual progression. Many patients can significantly improve their symptoms, prolong their lives, and enhance their quality of life through rehabilitation training and medication. However, there is no effective cure for Parkinson's disease at this time; current treatments only relieve symptoms and improve quality of life. Patients with Parkinson's should not be afraid and must regularly visit neurology outpatient clinics for follow-up. Neurologists will provide appropriate medications for Parkinson’s and guide the daily life of patients. Moreover, patients must prevent falls. Parkinson's is not a terrifying disease; what is dangerous is arbitrarily stopping or reducing medication without listening to the doctor's advice. (Note: This answer is for reference only, medication should be taken under the guidance of a professional physician, and medications should not be taken blindly.)

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Written by Zhang Hui
Neurology
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How long can someone with Parkinson's disease live?

Parkinson's disease is a degenerative disease of the nervous system. It has a slow and inconspicuous onset, and it progresses gradually. The disease itself does not affect the patient's lifespan, as it does not impact the functions of heartbeats or breathing. If treated properly, cared for promptly, medications are taken as prescribed by the doctor, and followed up long-term, patients can survive about twenty years without problems. However, if patients adjust their medications on their own, stop taking their medications without consultation, or receive improper care from family members leading to accidental injuries or complications such as lung infections, then their lifespan can be significantly shortened. Once bedridden, life expectancy may rapidly decline. Therefore, with proper treatment and care, patients with Parkinson's disease can survive for about ten to twenty years. If care and treatment are not managed properly, patients may be threatened by fractures or lung infections, potentially reducing their lifespan to about five to ten years.

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Can Parkinson's patients drink alcohol?

It is recommended that patients with Parkinson's disease avoid drinking alcohol. This is because the condition in Parkinson's patients is caused by the death of certain neurons in the substantia nigra of the midbrain. It is well-known that alcohol has a direct damaging effect on neurons. Therefore, drinking alcohol could potentially worsen the symptoms of Parkinson's disease, and it is advised not to drink alcohol. Additionally, patients with Parkinson's disease are prone to panic and unstable gait. If alcohol consumption affects the function of the cerebellum, it will exacerbate the patient's instability in walking, making them very prone to falls and potentially causing complications such as fractures. Furthermore, drinking alcohol can lead to orthostatic hypotension, which is a lower blood pressure when standing up. Parkinson's disease itself can also cause this type of orthostatic hypotension, and the combination of the two can cause a significant drop in blood pressure in patients, posing a risk when standing.