Can children with Tetralogy of Fallot heal on their own?

Written by Tong Peng
Pediatrics
Updated on April 15, 2025
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Children with Tetralogy of Fallot cannot be cured, as this condition is a congenital disease, primarily involving vascular malformations, characterized by ventricular septal defects, overriding aorta, pulmonary hypertension, and right ventricular hypertrophy.

Due to pulmonary atresia or near-atresia, leading to numerous collateral vessels, it might only present with a ventricular septal defect with shunting or mild pulmonary valve stenosis. The effectiveness of surgery for this type of Tetralogy of Fallot may not be particularly good, and the chances of a cure are very low.

Therefore, for this category, early detection and surgical treatment are crucial, and it is important to enhance dietary nutrition and care in daily life, as it is prone to pulmonary infections, which can lead to serious conditions such as respiratory failure and heart failure.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot cyanosis cause

Tetralogy of Fallot, due to a ventricular septal defect combined with right ventricular outflow tract narrowing, can display left-to-right, bidirectional, or even right-to-left shunting at the ventricular level. Patients with mild pulmonary stenosis can have left-to-right shunting and usually do not exhibit cyanosis. However, when the pulmonary stenosis is severe, significant right-to-left shunting occurs, and clinically apparent cyanosis becomes evident. Cyanosis is commonly observed in areas rich in capillaries and superficial tissues, such as the lips, fingertips, nail beds, and bulbar conjunctiva.

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Written by Hu Qi Feng
Pediatrics
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What position should be adopted when Tetralogy of Fallot is hypoxic?

Treatment of hypoxic episodes in Tetralogy of Fallot: For mild cases, assuming the knee-chest position can alleviate symptoms. Severe cases require immediate oxygen administration and relevant drug therapy. Routinely, it is important to actively eliminate factors that trigger hypoxic episodes, such as anemia and infections, and maintain the child's tranquility. If the above treatments do not effectively control the episodes, emergency surgical intervention for repair or definitive treatment should be considered.

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Written by Hu Qi Feng
Pediatrics
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The reason for squatting in Tetralogy of Fallot

The reason for squatting is that when squatting, the lower limbs are bent, which reduces the amount of blood returning to the heart through the veins, thereby reducing the load on the heart. At the same time, the arteries in the lower limbs are compressed, which increases the resistance in the systemic circulation and reduces the right-to-left shunt volume, allowing temporary relief from hypoxia symptoms. Babies who cannot walk often like to be held by adults in a position that bends the lower limbs to reduce the amount of blood returning to the heart. This frequently occurs during walking and playing, often characterized by brief periods of squatting.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot Emergency Measures

Generally, one should often drink water to prevent infection, prevent dehydration and complications. Infants and young children should be especially careful in their care, to avoid episodes of paroxysmal hypoxia. In mild cases of hypoxic episodes, placing them in a knee-chest position can alleviate the symptoms. In severe cases, oxygen should be administered immediately, along with the appropriate drug treatment. If the episodes cannot be effectively controlled with medication, emergency surgical intervention may be necessary. With the continuous improvement in surgical techniques this year, the mortality rate for curative surgeries has been decreasing.

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Written by Yan Xin Liang
Pediatrics
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The main cause of hypoxic attacks in Tetralogy of Fallot

Tetralogy of Fallot is a complex congenital heart disease, characterized by ventricular septal defect, right ventricular outflow tract obstruction, aorta overriding, and right ventricular hypertrophy. When the obstruction of the right ventricular outflow tract is severe, pulmonary artery blood flow significantly decreases. A large amount of unoxygenated venous blood passes through the ventricular septal defect causing a right-to-left shunt, which clinically manifests as severe cyanosis and increased red blood cells, and different degrees of hypoxia in the systemic circulation. Factors that can induce hypoxic episodes in these infants include feeding, crying, emotional agitation, anemia, infection, etc. These can suddenly lead to fainting, convulsions, or even death. The main reason is generally due to a sudden muscle spasm at the narrow pulmonary artery infundibulum on top of pre-existing stenosis, causing temporary pulmonary artery obstruction and exacerbating cerebral hypoxia, thus leading to severe hypoxic attacks.