Tetralogy of Fallot surgery success rate

Written by Yao Li Qin

Pediatrics

Updated on March 29, 2025

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Tetralogy of Fallot is a common cyanotic congenital heart disease in children after the age of one. It consists of four abnormalities: ventricular septal defect, obstruction of the right ventricular outflow tract, overriding aorta, and right ventricular hypertrophy. Once Tetralogy of Fallot is diagnosed, the ultimate treatment is surgical. With the development of pediatric cardiothoracic surgery, there are no specific requirements regarding the birth month or weight of the child for the surgery, so the success rate of Tetralogy of Fallot surgery is now very high. If a child has Tetralogy of Fallot, it is crucial to seek active treatment and not to give up.

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Written by Tong Peng

Pediatrics

55sec

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Does Tetralogy of Fallot easily lead to heart failure?

Tetralogy of Fallot often leads to symptoms of heart failure because it is a severe congenital disease. Affected children tend to present with cyanosis of the lips, impaired growth and development, and a simple echocardiography can reveal specific indicators such as aorta overriding, pulmonary stenosis, right ventricular hypertrophy, and ventricular septal defect. These children have limited lung and heart function, making them prone to increased cardiac load and symptoms of heart failure following infections or physical activity. Therefore, early surgical treatment is necessary for these children to prevent recurrent infectious diseases and heart failure, which can affect their normal growth and development. Additionally, it is crucial to enhance nutrition and exercise in their daily lives to boost their immune system. For Tetralogy of Fallot, early detection and treatment are essential.

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Written by Hu Qi Feng

Pediatrics

1min 12sec

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Tetralogy of Fallot Common Symptoms

The clinical manifestations of Tetralogy of Fallot include, firstly, cyanosis as the primary clinical symptom. The degree and onset of cyanosis are related to the severity of pulmonary stenosis, and it often appears in areas with abundant capillaries such as lips, fingers, toes, nail beds, and bulbar conjunctiva. Secondly, squatting symptoms are common among children; they often spontaneously squat for a while during walking or playing. Squatting, with the legs bent, reduces the venous return and thus decreases the load on the heart, temporarily relieving symptoms of hypoxia by reducing the right-to-left shunt. Thirdly, clubbing occurs due to long-term hypoxic conditions, which can cause capillary dilation and proliferation in the fingers and toes, and the local soft tissues and bones also grow and enlarge; fourthly, paroxysmal hypoxic attacks, which are most common in infants, can be triggered by breastfeeding, crying, emotional excitement, or anemia. These attacks suddenly occur and can lead to severe symptoms including difficulty breathing, fainting, convulsions, and even death.

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Written by Yan Xin Liang

Pediatrics

43sec

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Tetralogy of Fallot shadow on the radiograph

Tetralogy of Fallot is the most common cyanotic heart disease in children over the age of one, accounting for about 10 percent of all congenital heart diseases. Tetralogy of Fallot includes four anatomical abnormalities: a ventricular septal defect, right ventricular outflow tract obstruction, an overriding aorta, and right ventricular hypertrophy. In patients diagnosed through X-ray, the heart size is often within normal limits, typically appearing boot-shaped, with markedly reduced pulmonary vascular markings. The aortic arch may be located on the right side, and the ascending aorta is usually dilated. Patients with rich collateral circulation display prominent pulmonary markings.

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Written by Chen Guang Yin

Cardiology

44sec

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Does Tetralogy of Fallot involve chromosomal abnormalities?

Tetralogy of Fallot is primarily a developmental disorder, generally unrelated to chromosomes, with no chromosomal abnormalities. The cause of the disease is still not very clear. If pregnant again and giving birth again, it generally does not recur. Therefore, couples undergoing chromosomal testing before pregnancy is a common practice. It is generally believed that the four malformations in Tetralogy of Fallot occur due to viral infections acquired by the fetus during pregnancy, the mother consuming alcohol, or the use of certain medications during pregnancy. Currently, these are considered related factors, and so far, no abnormalities have been found related to genetics or chromosomes.

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Written by Yan Xin Liang

Pediatrics

38sec

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Is Tetralogy of Fallot hereditary?

Tetralogy of Fallot is a common cyanotic congenital heart disease in children, accounting for about ten percent of congenital heart diseases. It primarily consists of four abnormalities: ventricular septal defect, right ventricular outflow tract obstruction, overriding aorta, and left ventricular hypertrophy. Congenital heart disease is not a hereditary disease; it is not controlled by genes, mainly due to abnormal development of the heart and blood vessels during fetal development, leading to cardiovascular malformations. Thus, this disease is not hereditary.