Tetralogy of Fallot Clinical Symptoms

Written by Hu Qi Feng
Pediatrics
Updated on September 14, 2024
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The clinical manifestations of Tetralogy of Fallot include cyanosis, with cyanosis being the primary symptom. The severity of cyanosis is related to the extent of pulmonary stenosis and is commonly seen in areas rich in capillaries, such as the lips, fingertips, nail beds, and conjunctiva, where it appears more pronounced during physical activity or crying. Secondly, the squatting symptom is observed; children may show squatting behavior during walking or playing, often squatting down voluntarily for a moment. During squatting, the flexion of the lower limbs reduces the venous return to the heart, lightening the cardiac load and decreasing the right-to-left shunting, thereby alleviating hypoxia. Thirdly, clubbing of the fingers occurs due to long-term hypoxia, leading to hypertrophic growth at the fingertip and toe ends. Fourthly, paroxysmal hypoxic attacks occur.

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Written by Tong Peng
Pediatrics
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Can children with Tetralogy of Fallot heal on their own?

Children with Tetralogy of Fallot cannot be cured, as this condition is a congenital disease, primarily involving vascular malformations, characterized by ventricular septal defects, overriding aorta, pulmonary hypertension, and right ventricular hypertrophy. Due to pulmonary atresia or near-atresia, leading to numerous collateral vessels, it might only present with a ventricular septal defect with shunting or mild pulmonary valve stenosis. The effectiveness of surgery for this type of Tetralogy of Fallot may not be particularly good, and the chances of a cure are very low. Therefore, for this category, early detection and surgical treatment are crucial, and it is important to enhance dietary nutrition and care in daily life, as it is prone to pulmonary infections, which can lead to serious conditions such as respiratory failure and heart failure.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot symptoms in infants

Infants with Tetralogy of Fallot often exhibit the following symptoms: First, cyanosis, which is most apparent in areas rich in capillaries such as the lips, fingernail beds, and conjunctiva. Cyanosis tends to worsen gradually during crying, emotional distress, or physical exertion. Second, squatting symptoms; infants who cannot walk often prefer to be held by adults in a flexed position of both lower limbs, reducing venous return and easing the cardiac workload. Older children often exhibit squatting during activities such as walking and playing, frequently squatting down momentarily. Third, infants in a prolonged hypoxic environment may develop clubbing, characterized by the enlargement of the fingertips and toes, with capillary expansion and proliferation, resembling drumsticks. Fourth, episodic hypoxia occurs predominantly in infants, triggered by feeding, crying, or emotional distress, manifesting as episodes of respiratory difficulty, with severe cases leading to sudden fainting or convulsions.

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Written by Hu Qi Feng
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Tetralogy of Fallot syncope causes

The causes of syncope in Tetralogy of Fallot generally involve episodic hypoxia attacks, which are more common in infants. Triggers include breastfeeding, crying, emotional excitement, anemia, and infections. The symptoms manifest as episodic breathing difficulties, and severe cases can suddenly lead to syncope with convulsions or even death. The underlying reason is the narrowing of the pulmonary artery infundibulum accompanied by muscular spasms, causing obstruction of the pulmonary artery and intensifying cerebral hypoxia. Older children may complain of headaches and dizziness.

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Written by Hu Qi Feng
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Tetralogy of Fallot is what?

Tetralogy of Fallot is the most common cyanotic congenital heart disease in infants, accounting for about twelve percent of all congenital heart diseases. It was thoroughly described by the French physician Fallot in 1888, which is how it got its name. Tetralogy of Fallot consists of four cardiac malformations: first, obstruction of the right ventricular outflow tract; second, ventricular septal defect; third, overriding aorta; fourth, right ventricular hypertrophy.

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Management of Hypoxic Episodes in Children with Tetralogy of Fallot

In the treatment of hypoxic episodes in children with Tetralogy of Fallot, mild cases can be alleviated by positioning the child in a knee-chest position, while severe cases should receive immediate oxygen therapy, along with appropriate medication to correct acidosis. It is important to regularly eliminate factors that may trigger hypoxic episodes, such as anemia and infections, and to maintain a calm environment for the child. If these measures do not effectively control the episodes, emergency surgical repair should be considered.