Can Tetralogy of Fallot be cured?

Written by Hu Qi Feng
Pediatrics
Updated on September 30, 2024
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With the continuous improvement of surgical techniques, the cure rate for total corrective surgery for Tetralogy of Fallot is increasing, and the mortality rate is continuously decreasing. Mild cases may have the opportunity to undergo a one-stage corrective surgery between the ages of five and nine. However, for patients with significant clinical symptoms, palliative surgery should be performed within six months after birth. Once the general condition improves and pulmonary vasculature develops, they can proceed with the corrective surgery. Overall, the cure rate for Tetralogy of Fallot is continuously improving.

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Written by Yao Li Qin
Pediatrics
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Can Tetralogy of Fallot be cured?

Tetralogy of Fallot is a type of congenital heart disease linked to family genetics and is considered quite severe among congenital heart conditions. Generally, within a few months after birth, children will exhibit cyanosis of the skin. It is crucial to perform surgery on the child promptly in such cases. Currently, the level of pediatric cardiothoracic surgery in our country has developed very rapidly. For typical cases of Tetralogy of Fallot, surgical treatment can be curative. Moreover, there are no specific requirements regarding weight and age for children undergoing heart surgery nowadays. Therefore, once Tetralogy of Fallot is diagnosed in young children, it is best to perform surgery as soon as possible. These children can then grow up, develop normally, and attend school like their peers.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot Clinical Symptoms

The clinical manifestations of Tetralogy of Fallot include cyanosis, with cyanosis being the primary symptom. The severity of cyanosis is related to the extent of pulmonary stenosis and is commonly seen in areas rich in capillaries, such as the lips, fingertips, nail beds, and conjunctiva, where it appears more pronounced during physical activity or crying. Secondly, the squatting symptom is observed; children may show squatting behavior during walking or playing, often squatting down voluntarily for a moment. During squatting, the flexion of the lower limbs reduces the venous return to the heart, lightening the cardiac load and decreasing the right-to-left shunting, thereby alleviating hypoxia. Thirdly, clubbing of the fingers occurs due to long-term hypoxia, leading to hypertrophic growth at the fingertip and toe ends. Fourthly, paroxysmal hypoxic attacks occur.

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Written by Chen Guang Yin
Cardiology
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Can Tetralogy of Fallot receive oxygen therapy?

Tetralogy of Fallot is a congenital heart defect that includes abnormalities such as ventricular septal defects, pulmonary valve stenosis, and stenosis of the right ventricular outflow tract. Due to these congenital defects, the ejection of blood from the heart is affected, which in turn impacts the blood supply to various systems and organs throughout the body. The patient may exhibit symptoms of cyanosis and hypoxia, especially after physical activity, hence the use of supplemental oxygen is advisable. While oxygen therapy can temporarily alleviate these hypoxic symptoms, it does not address the underlying issue. Surgery is necessary for a definitive resolution.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot syncope causes

The causes of syncope in Tetralogy of Fallot generally involve episodic hypoxia attacks, which are more common in infants. Triggers include breastfeeding, crying, emotional excitement, anemia, and infections. The symptoms manifest as episodic breathing difficulties, and severe cases can suddenly lead to syncope with convulsions or even death. The underlying reason is the narrowing of the pulmonary artery infundibulum accompanied by muscular spasms, causing obstruction of the pulmonary artery and intensifying cerebral hypoxia. Older children may complain of headaches and dizziness.

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Written by Tong Peng
Pediatrics
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Can children with Tetralogy of Fallot heal on their own?

Children with Tetralogy of Fallot cannot be cured, as this condition is a congenital disease, primarily involving vascular malformations, characterized by ventricular septal defects, overriding aorta, pulmonary hypertension, and right ventricular hypertrophy. Due to pulmonary atresia or near-atresia, leading to numerous collateral vessels, it might only present with a ventricular septal defect with shunting or mild pulmonary valve stenosis. The effectiveness of surgery for this type of Tetralogy of Fallot may not be particularly good, and the chances of a cure are very low. Therefore, for this category, early detection and surgical treatment are crucial, and it is important to enhance dietary nutrition and care in daily life, as it is prone to pulmonary infections, which can lead to serious conditions such as respiratory failure and heart failure.