Medications for treating gastric ulcers

Written by Wang Hui Jie
Gastroenterology
Updated on September 20, 2024
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Here I will introduce several major types of medications for treating gastric ulcers, but specific medication use should be consulted with a doctor or pharmacist according to individual conditions. The first major type is anti-gastric acid medications. Since gastric acid plays a significant role in ulcerative lesions, it is considered appropriate to treat gastric ulcers by adjusting the stomach environment to a pH of 3.5. Anti-acid medications include antacids, H2 receptor antagonists, proton pump inhibitors, and others. The second major type is gastric mucosal protectants, which include some class B drugs, prostaglandin derivatives, and some containing sucralfate. The third major type is medications that treat Helicobacter pylori, with quadruple therapy currently being a common practice. Note: Medications should be used under the guidance of a doctor.

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Written by Wang Hui Jie
Gastroenterology
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Medications for treating gastric ulcers

Here I will introduce several major types of medications for treating gastric ulcers, but specific medication use should be consulted with a doctor or pharmacist according to individual conditions. The first major type is anti-gastric acid medications. Since gastric acid plays a significant role in ulcerative lesions, it is considered appropriate to treat gastric ulcers by adjusting the stomach environment to a pH of 3.5. Anti-acid medications include antacids, H2 receptor antagonists, proton pump inhibitors, and others. The second major type is gastric mucosal protectants, which include some class B drugs, prostaglandin derivatives, and some containing sucralfate. The third major type is medications that treat Helicobacter pylori, with quadruple therapy currently being a common practice. Note: Medications should be used under the guidance of a doctor.

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Written by Li Xue Qing
Gastroenterology
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How to treat gastric ulcers?

The treatment of gastric ulcers mainly consists of general management and pharmacotherapy. General management involves patients avoiding spicy, stimulating, and cold foods, eating regular meals, and avoiding medications that may harm the stomach, such as non-steroidal anti-inflammatory drugs. Pharmacotherapy mainly includes gastroprotective therapy and treatment against Helicobacter pylori. Gastroprotective therapy includes neutralizing stomach acid with agents such as magnesium carbonate chewing tablets, acid-suppressing medications like proton pump inhibitors and H2 receptor antagonists, pantoprazole, cimetidine, etc. Medications to protect the gastric mucosa, such as sucralfate, bismuth preparations, etc., are also used. Treatment against Helicobacter pylori mainly includes triple and quadruple therapy. Triple therapy involves a proton pump inhibitor or a bismuth agent combined with two types of antibiotics, and quadruple therapy consists of a proton pump inhibitor, a bismuth agent, and two types of antibiotics. Antibiotics commonly used include amoxicillin, clarithromycin, furazolidone, levofloxacin, metronidazole, tetracycline, etc. Treatment generally lasts seven to ten days, with overall therapy for gastric ulcers spanning about a month. (Please undertake any medication under the guidance of a doctor.)

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Written by Jiang Guo Ming
Gastroenterology
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Can gastric ulcers be cured?

Gastric ulcers are classified into benign and malignant types. Most duodenal bulb ulcers and gastric ulcers are benign and can be cured through medication. Treatment plans are usually determined based on the presence of Helicobacter pylori infection. Patients with Helicobacter pylori infection can be treated with antibacterial therapy. If there is no infection, symptomatic treatment alone is generally sufficient for a cure. If the ulcer is malignant or is a giant ulcer, surgical treatment is generally required. For those who cannot undergo surgery, radiotherapy or chemotherapy may be needed. Generally, the prognosis for malignant ulcers is worse than for benign ulcers.

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Written by Li Xue Qing
Gastroenterology
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What foods to eat for gastric ulcers?

People with stomach ulcers should eat foods that are easy to digest and high in protein and vitamins, such as soft rice, porridge, and noodles. Foods rich in protein include fish, milk, and walnuts. Foods high in vitamins include tomatoes, carrots, bean sprouts, and spinach. Patients with stomach ulcers should avoid spicy and stimulating foods such as chili peppers, garlic, leeks, and ginger, as well as seasonings like cinnamon, star anise, and Sichuan pepper. They should also avoid overly acidic foods, raw and cold foods, fried foods, and foods that are high in rough fiber.

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Written by Si Li Li
Gastroenterology
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What should not be eaten with gastric ulcers?

Patients with gastric ulcers should be cautious about their diet, abstain from smoking and alcohol, and avoid drinking strong tea, coffee, eating fatty, greasy, spicy, fried, barbecued, raw, cold, and sweet foods, as well as drinking milk and soy milk, or eating glutinous rice and sweet potatoes. This is because some of these foods can stimulate the secretion of gastric acid, worsening the irritation of gastric mucosa and exacerbating gastric ulcers. Some are difficult to digest, thus, they are not recommended. It is advisable to eat porridge, drink soups, eat noodles, such as millet porridge, yam porridge, barley porridge, chicken soup, and pork rib soup. When eating meats, ensure they are well-stewed before consumption.