How to supplement for anemia in diabetic nephropathy?

Written by Zhou Qi
Nephrology
Updated on September 04, 2024
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Patients with diabetic nephropathy who exhibit anemia are often in a state of chronic renal failure. This anemia caused by chronic kidney disease is mainly due to the decreased secretion of erythropoietin by the kidneys. Therefore, treatment involves the use of erythropoietin to stimulate bone marrow hematopoiesis. In addition to this medication, patients generally also need to supplement with iron preparations, such as ferrous succinate, sucrose iron, etc., and take oral folic acid, all of which are raw materials for blood formation. Furthermore, if patients have severe malnutrition, they should also supplement with foods rich in protein, such as eggs, milk, chicken, duck, fish, etc. (Please use medications under the guidance of a doctor.)

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Written by Zhou Qi
Nephrology
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Does diabetic nephropathy hurt?

Diabetic nephropathy generally does not cause painful symptoms. Diabetic nephropathy refers to the kidney damage that results from long-term diabetes, caused by factors such as hyperglycemia, oxidative stress, and an increase in advanced glycation end products. In the early stages, patients may experience an increase in kidney size and an increased glomerular filtration rate. As the condition progresses, proteinuria may occur, and it could eventually lead to severe renal failure. Throughout this process, patients typically do not experience pain because the kidneys do not have nerve innervation and therefore do not feel pain. Thus, including diabetic nephropathy, various kidney diseases and nephritis generally do not manifest with pain.

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Written by Pan Wu Shan
Nephrology
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Can people with diabetic nephropathy eat peanuts?

Diabetic nephropathy, as the name suggests, is a renal complication caused by long-term diabetes. The typical early symptom is a significant amount of proteinuria, which can usually be detected as high protein levels during routine urine tests. If it progresses to a late stage, the substantial amount of proteinuria can lead to general edema and possibly heart failure. Currently, there is no particularly effective treatment for diabetic nephropathy. The primary approach is to control blood sugar levels, keeping fasting blood glucose below 7 and postprandial glucose below 10. Diet-wise, it's important to consume low-salt, low-fat, diabetic-friendly foods. Daily salt intake should not exceed three grams. Foods that are fried, greasy, or high in starch, such as vermicelli, sweet potatoes, taro, and potatoes should be consumed in moderation. Peanuts, which are high in oil content, can be eaten in small amounts but not excessively, as they may also cause indigestion.

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Written by Zhou Qi
Nephrology
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Symptoms of stage four diabetic nephropathy

Stage four of diabetic nephropathy indicates the presence of significant amounts of urinary protein. At this stage, patients may exhibit symptoms of nephrotic syndrome, which means the total urinary protein quantification over 24 hours may exceed 3.5 grams, and the plasma albumin level may be lower than 30 grams per liter. Due to the large amount of protein leakage, patients may experience edema, presenting as swelling of the lower limbs or eyelids, or even severe generalized swelling. In addition to edema, patients may also have pleural and abdominal effusion, leading to pulmonary edema. Excessive fluid can overburden the heart, causing heart failure, which manifests as chest tightness, shortness of breath, and difficulty breathing, especially when the patient is active, these symptoms of chest tightness and shortness of breath become more pronounced.

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Written by Zhou Qi
Nephrology
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Can diabetic nephropathy undergo kidney transplantation?

Diabetic nephropathy has now become the leading cause of uremia in China, accounting for the largest proportion. In the 1980s and 1990s, chronic nephritis was the most common cause of uremia in China. Over the past decade, diabetic nephropathy has gradually surpassed chronic nephritis and become the leading condition. This condition requires dialysis or a kidney transplant when it progresses to uremia. Patients with diabetic nephropathy in a uremic state can undergo a kidney transplant. After the transplant, these patients still need to use medications to control their blood sugar and blood pressure, to prevent high blood sugar and high blood pressure from further damaging the new kidney. Of course, if conditions allow, performing a combined kidney and pancreas transplant might yield better results.

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Written by Zhou Qi
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How to reduce proteinuria in diabetic nephropathy.

A major clinical feature of diabetic nephropathy is the occurrence of proteinuria, which, if the condition continues to progress, can lead to kidney failure. Controlling proteinuria in the early stages of the disease is indeed very important. In terms of treatment, it is primarily necessary to use medications or insulin to control the patient's blood sugar, as hyperglycemia is the fundamental cause of diabetic nephropathy. Additionally, these patients often also have hypertension, necessitating the use of antihypertensive drugs to control blood pressure. When the patient's kidney function is not severely impaired, ACE inhibitors or ARBs can be the preferred choice of antihypertensive drugs, as they not only control blood pressure but also reduce proteinuria. However, if the patient's serum creatinine is significantly elevated, such as over 264 µmol/L, these drugs should no longer be used. (Medications should be used under the guidance of a doctor.)