How to supplement for anemia in diabetic nephropathy?

Written by Zhou Qi
Nephrology
Updated on September 04, 2024
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Patients with diabetic nephropathy who exhibit anemia are often in a state of chronic renal failure. This anemia caused by chronic kidney disease is mainly due to the decreased secretion of erythropoietin by the kidneys. Therefore, treatment involves the use of erythropoietin to stimulate bone marrow hematopoiesis. In addition to this medication, patients generally also need to supplement with iron preparations, such as ferrous succinate, sucrose iron, etc., and take oral folic acid, all of which are raw materials for blood formation. Furthermore, if patients have severe malnutrition, they should also supplement with foods rich in protein, such as eggs, milk, chicken, duck, fish, etc. (Please use medications under the guidance of a doctor.)

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Written by Zhou Qi
Nephrology
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Late-stage symptoms of diabetic nephropathy

When patients with diabetic nephropathy reach the advanced stage, they actually already have severe renal failure. Prior to this, patients generally exhibit noticeable proteinuria. Continued progression of the disease will lead to the destruction of most of the renal tissues, causing renal failure. This condition is quite serious; patients often experience significant edema, even severe generalized edema. The accumulation of a large amount of fluid in the body leads to an increase in blood volume, and both the preload and afterload on the heart increase, often accompanied by symptoms of heart failure. When patients experience heart failure, they may find it impossible to lie flat and may experience chest tightness, shortness of breath, and difficulty breathing after activity, potentially endangering their lives.

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Written by Zhou Qi
Nephrology
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Symptoms of stage four diabetic nephropathy

Stage four of diabetic nephropathy indicates the presence of significant amounts of urinary protein. At this stage, patients may exhibit symptoms of nephrotic syndrome, which means the total urinary protein quantification over 24 hours may exceed 3.5 grams, and the plasma albumin level may be lower than 30 grams per liter. Due to the large amount of protein leakage, patients may experience edema, presenting as swelling of the lower limbs or eyelids, or even severe generalized swelling. In addition to edema, patients may also have pleural and abdominal effusion, leading to pulmonary edema. Excessive fluid can overburden the heart, causing heart failure, which manifests as chest tightness, shortness of breath, and difficulty breathing, especially when the patient is active, these symptoms of chest tightness and shortness of breath become more pronounced.

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Written by Zhou Qi
Nephrology
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How to reduce proteinuria in diabetic nephropathy.

A major clinical feature of diabetic nephropathy is the occurrence of proteinuria, which, if the condition continues to progress, can lead to kidney failure. Controlling proteinuria in the early stages of the disease is indeed very important. In terms of treatment, it is primarily necessary to use medications or insulin to control the patient's blood sugar, as hyperglycemia is the fundamental cause of diabetic nephropathy. Additionally, these patients often also have hypertension, necessitating the use of antihypertensive drugs to control blood pressure. When the patient's kidney function is not severely impaired, ACE inhibitors or ARBs can be the preferred choice of antihypertensive drugs, as they not only control blood pressure but also reduce proteinuria. However, if the patient's serum creatinine is significantly elevated, such as over 264 µmol/L, these drugs should no longer be used. (Medications should be used under the guidance of a doctor.)

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Written by Pan Wu Shan
Nephrology
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Can people with diabetic nephropathy drink alcohol?

Diabetic nephropathy, as the name suggests, is a complication caused by diabetes that leads to kidney problems. The typical symptoms of diabetic nephropathy are significant proteinuria and hypoalbuminemia. Generally speaking, there is no particularly effective treatment for diabetic nephropathy; it can only be managed by keeping blood sugar and blood pressure under control. For patients with diabetic nephropathy, it is recommended to keep fasting blood glucose below 7, and postprandial glucose should be controlled between 8 and 10, which is considered appropriate. If hypertension is present, blood pressure should be kept below 140/80 mmHg. In terms of diet, patients with diabetic nephropathy definitely should not drink alcohol, and they should avoid sweets, fried foods, and foods high in starch. It is also important not to stay up late.

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How many years can a person with diabetic nephropathy live?

Diabetic nephropathy is divided into several stages, from mild to severe. In the early stage, patients only have an increased glomerular filtration rate and the proteinuria is not significant. As the disease progresses, the protein in the urine increases, eventually leading to renal failure and even developing into uremia. The entire process can last many years, with some patients experiencing it for up to ten years. In fact, when diabetic nephropathy progresses to its final stage, uremia, patients still have many treatment options, such as hemodialysis, peritoneal dialysis, or kidney transplantation, and even combined kidney and pancreas transplantation. Therefore, how long a patient can live depends on the patient's age, presence of cardiovascular and cerebrovascular diseases, and the choice of treatment methods, among other factors.