Rheumatic heart disease is not hereditary, and it is not a genetic disease; it is not directly related to genetics. It is mainly due to an abnormal immune response caused by streptococcal infection, which leads to damage to the heart valves, resulting in stenosis and insufficiency of the heart valves. It is possible to prevent the occurrence of rheumatic heart disease. Very rare rheumatic streptococcal infections can be reduced by using effective antibiotics to control the streptococcal infection. Common diseases that cause streptococcal infections include tonsillitis and upper respiratory tract infections. Once tonsillitis or an upper respiratory tract infection occurs, effective antibiotics should be used to control the infection as soon as possible.