Can rheumatic heart disease be inherited?

Written by Zhang Yue Mei
Cardiology
Updated on September 26, 2024
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Rheumatic heart disease is not hereditary and it is not a genetic disease. Rheumatic heart disease is a hypersensitivity disease caused by an infection, especially following a streptococcal infection. This type of infection leads to the body producing antibodies. In some individuals, these antibodies combine with antigens, causing inflammation of the collagen tissue and affecting the heart. This results in inflammatory lesions on the heart valves, causing the valves to become narrowed or fail to close completely, leading to pathological changes known as rheumatic heart disease.

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Can rheumatic heart disease with enlarged heart be treated with surgery?

Patients with rheumatic heart disease generally present with valvular insufficiency or severe stenosis. If the patient's heart is enlarged and the ejection fraction significantly decreases, for example, if the left ventricular diastolic diameter is greater than 75, and the ejection fraction is less than 30%, the surgical outcome may be poor. This is particularly the case if there is associated pulmonary arterial hypertension, which may lead to no improvement in condition after surgery, indicating a poor surgical outcome. However, if the patient has severe stenosis or insufficiency of the valve function, not performing surgery could further worsen the condition.

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Written by Chen Tian Hua
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What to do about reduced urine output in the late stage of rheumatic heart disease?

Patients with rheumatic heart disease who experience oliguria in the late stage should consider the possibility of heart failure as the cause. Due to heart failure leading to a decrease in cardiac output, renal blood perfusion is reduced, which in turn causes symptoms of oliguria. Additionally, if the patient also has renal function impairment, it will further exacerbate the symptoms of oliguria. It is important for patients with rheumatic heart disease who experience symptoms of oliguria to seek medical attention promptly and receive active treatment as soon as possible. Medications to control heart failure should be administered to increase the heart's contractility and cardiac output, improve renal perfusion, and diuretics should be given to increase urine output. With heart failure under control, the patient's condition can be alleviated. For patients with rheumatic heart disease, if there are indications for surgery, timely surgical treatment should be provided.

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Written by Zhang Yue Mei
Cardiology
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Is rheumatic heart disease hereditary?

Rheumatic heart disease is not hereditary, and it is not a genetic disease; it is not directly related to genetics. It is mainly due to an abnormal immune response caused by streptococcal infection, which leads to damage to the heart valves, resulting in stenosis and insufficiency of the heart valves. It is possible to prevent the occurrence of rheumatic heart disease. Very rare rheumatic streptococcal infections can be reduced by using effective antibiotics to control the streptococcal infection. Common diseases that cause streptococcal infections include tonsillitis and upper respiratory tract infections. Once tonsillitis or an upper respiratory tract infection occurs, effective antibiotics should be used to control the infection as soon as possible.

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Written by Xie Zhi Hong
Cardiology
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The causes of syncope in rheumatic heart disease.

The most common manifestation of rheumatic heart disease involves the mitral valve, leading to severe stenosis and insufficiency of the mitral valve, and decreasing the amount of blood returning to the heart. At this time, there is not enough blood returning to the heart, and naturally, the amount of blood pumped out is reduced. If it is extremely severe, it can lead to fainting; this is the first scenario. The second scenario is rheumatic heart disease affecting the aortic valve, which can also result in insufficient blood being pumped out, causing ischemia and hypoxia in the cerebral arteries, leading to fainting. Another situation is related to heart arrhythmias, which are divided into two types. One type occurs when rheumatic heart disease is very severe, potentially causing atrial fibrillation. Some patients with cardiac bypass might experience ventricular fibrillation, leading to fainting. Additionally, there is a scenario where severe rheumatic inflammation causes dysfunction in the heart's conduction system, leading to conditions similar to sick sinus syndrome or complete atrioventricular block, causing significantly slow heart rhythms, which may also lead to fainting.

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What should I do if rheumatic heart disease causes excessive sweating?

If patients frequently experience heart murmurs in the precordial area due to rheumatic heart disease, accompanied by palpitations, chest tightness, and sweating, it is recommended to treat with infusion therapy and use medication to control the patient's heart function. If the patient's heart function is corrected, the symptoms of sweating will also be alleviated or relieved. It is advised that patients visit a cardiology department and choose hospitalization to improve their symptoms. After treatment, long-term and regular oral medication is still needed, as this disease is prone to recurrence. Regular hospital visits for electrocardiograms and echocardiograms are also necessary. If the symptoms are severe, sometimes surgical treatment may be recommended to relieve the current sweating symptoms.