Can arteriosclerosis be cured?

Written by Chen Ya
Geriatrics
Updated on September 11, 2024
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Atherosclerosis can only slow down its further progression and prevent the further occurrence of conditions such as coronary heart disease, cerebral infarction, and lower limb arterial occlusion. This is because it is influenced by many factors, including both modifiable and non-modifiable risk factors. For example, modifiable factors include abnormal blood lipids, hypertension, diabetes, smoking, and overweight obesity, which we can change. However, there are also non-modifiable factors such as age, genetics, and environmental factors. As age increases, the incidence of atherosclerosis significantly rises. Its pathological changes generally begin in childhood or adolescence, with symptoms becoming more apparent as age progresses.

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Written by Chen Ya
Geriatrics
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The difference between arteriosclerosis and atherosclerosis

Arteriosclerosis is a common and important type among a group of vascular diseases known as arteriosclerosis. The common characteristics of various arterioscleroses include thickening and hardening of arterial walls, loss of elasticity, and narrowing of the lumen. Atherosclerosis is a type of arteriosclerosis characterized by lesions starting from the arterial intima, subsequently involving the accumulation of lipids and complex carbohydrates, bleeding, thrombosis, proliferation of fibrous tissues, and deposition of calcium, along with gradual degeneration and calcification of the arterial media. Since the lipids accumulated in the arterial intima appear yellowish and mushy, it is termed atherosclerosis.

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Written by Zeng Wei Jie
Cardiology
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Treatment of Arteriosclerosis

The treatment of arteriosclerosis includes general preventative measures, pharmacological treatment, interventional procedures, and surgical operations. General precautions involve a balanced diet, with some patients needing to lose weight, increasing the intake of fruits and vegetables, quitting smoking and limiting alcohol consumption, and adopting a low-fat diet. Additionally, it is advised that patients engage in appropriate physical labor and sports activities, while also maintaining an optimistic and calm mindset. Pharmacological treatment is quite specialized, mainly including lipid-lowering and antiplatelet therapies. Then, there are cases with clear symptoms, such as renal artery stenosis or coronary artery narrowing, where interventional treatments can be considered. For those unsuitable for interventional procedures, surgical treatments, such as bypass surgery, might be considered.

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Written by Tang Li
Cardiology
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Causes of arteriosclerosis

The etiology of arteriosclerosis has not been fully determined, and studies indicate that arteriosclerosis is a multifactorial disease, caused by multiple factors acting at different stages, which are referred to as risk factors. The primary risk factors include the following: First, age and gender. Clinically, it is more common in middle-aged and elderly people over forty years old. After the age of forty-nine, the progression is fast, but early arteriosclerotic changes have also been found in autopsy of some young adults and even children. In recent years, clinical onset age tends to be younger. Compared to men, the incidence rate in women is lower, because estrogen has a protective effect against arteriosclerosis. Therefore, the incidence rate in women increases rapidly after menopause. Age and gender are unchangeable risk factors. Second, abnormal lipid levels, with abnormal lipid metabolism being the most important risk factor for arteriosclerosis. Third, hypertension, as the incidence of arteriosclerosis in patients with hypertension is significantly higher. Sixty to seventy percent of patients with coronary arteriosclerosis have hypertension, and patients with hypertension are three to four times more likely to have arteriosclerosis compared to those with normal blood pressure. Fourth, smoking, as the incidence and mortality rate of coronary arteriosclerosis in smokers are two to six times higher than in non-smokers, and it correlates positively with the number of cigarettes smoked daily. Secondhand smoke is also a risk factor. Fifth, diabetes and glucose intolerance, where not only is the incidence of arteriosclerosis in diabetic patients several times higher than in non-diabetics, but the progression of the disease is also rapid. Sixth, obesity, defined as being more than twenty percent over the standard weight or a BMI greater than twenty-four. Obesity is also a risk factor for arteriosclerosis. Seventh, family history, where a family history of coronary heart disease, diabetes, hypertension, and hyperlipidemia significantly increases the incidence of coronary heart disease. Various theories have been proposed to explain the pathogenesis of coronary arteriosclerosis from different perspectives. These include the lipid infiltration theory, thrombosis theory, and smooth muscle cell clonal theory. In recent years, the endothelial damage response theory has gained more support, suggesting that the disease results from various risk factors ultimately damaging the arterial intima, and the formation of arteriosclerosis lesions is an inflammatory, fibro-proliferative response of the arteries to endothelial damage.

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Written by Chen Ya
Geriatrics
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How long can one live with arteriosclerosis?

Arteriosclerosis has a certain impact on survival and longevity, but it is not an absolute determinant. People with mild arteriosclerosis have fewer sudden incidents of cerebral infarction and myocardial infarction, thus they may have a longer survival period. However, if arteriosclerosis leads to myocardial infarction or cerebral infarction, it will also affect their lifespan, but there is no absolute conclusion.

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Written by Tang Li
Cardiology
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The difference between arteriosclerosis and atherosclerosis.

Arteriosclerosis and atherosclerosis are two different concepts. Arteriosclerosis is a type of vascular disease within arteriosclerosis, but atherosclerosis is more commonly significant clinically. Hence, it is customarily referred to simply as arteriosclerosis, generally implying atherosclerosis. The causes of arteriosclerosis are numerous, but they share common characteristics including thickening, hardening, loss of elasticity, and narrowing of the arterial walls. Atherosclerosis is characterized by lesions starting in the innermost layer of the artery, involving local accumulation of lipids, complex carbohydrates, fibrous tissue proliferation, and calcification forming plaques, along with a gradual degeneration of the innermost layer. The lipid accumulation gives the inner layer a yellowish, porridge-like appearance, hence the name atherosclerosis.