Can arteriosclerosis be cured?

Written by Chen Ya
Geriatrics
Updated on September 11, 2024
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Atherosclerosis can only slow down its further progression and prevent the further occurrence of conditions such as coronary heart disease, cerebral infarction, and lower limb arterial occlusion. This is because it is influenced by many factors, including both modifiable and non-modifiable risk factors. For example, modifiable factors include abnormal blood lipids, hypertension, diabetes, smoking, and overweight obesity, which we can change. However, there are also non-modifiable factors such as age, genetics, and environmental factors. As age increases, the incidence of atherosclerosis significantly rises. Its pathological changes generally begin in childhood or adolescence, with symptoms becoming more apparent as age progresses.

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Written by Zeng Wei Jie
Cardiology
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How to eliminate atherosclerotic plaques?

Arterial plaques associated with atherosclerosis are generally impossible to completely eliminate, but it is feasible to prevent the progression of the disease and strive for stable reversal. Achieving stability and reversal involves a balanced diet, appropriate physical and athletic activity, maintaining a positive mood, quitting smoking and limiting alcohol consumption, and actively controlling hypertension, diabetes, dyslipidemia, and obesity. Additionally, some medications that stabilize plaques may be necessary, mainly including lipid-modifying statins. For patients with soft plaques who are at risk of acute cardiovascular events, it may also be necessary to take anti-vascular medications. For those already showing signs of organ ischemia, interventional or surgical treatment may even be needed. (Please use medications under the guidance of a doctor.)

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Cardiology
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How is arteriosclerosis treated?

The treatment of arteriosclerosis includes general preventive measures, pharmacological treatment interventions, and surgical interventions. General protective measures include reasonable dietary practices, appropriate physical exercise, proper arrangement of work and life, maintaining a pleasant mood, quitting smoking, limiting alcohol consumption, and controlling some disease-related risk factors such as hypertension, diabetes, dyslipidemia, obesity, etc. The main pharmacological treatment focuses on lipid-lowering and antiplatelet medication. For some patients with symptoms of angina pectoris, such as symptoms of target organ damage, treatment may involve dilating the blood vessels. Interventional treatment indications are now relatively broad. For some who are not suitable for interventional procedures, surgical treatments can be considered.

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Written by Zeng Wei Jie
Cardiology
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Arteriosclerosis is divided into several stages.

Arterial atherosclerosis sequentially manifests as three major types: lipid spots and stripes, atheromatous and fibrous atheromatous plaques, and complex lesions. According to the process of its occurrence and development, it can be subdivided into six types. The first type is lipid spots, which are small yellow spots on the arterial intima that gradually develop into the second type, lipid stripes, where some yellow stripes appear on the arterial intima. Then there is the third type, pre-lesional plaque, where more lipid droplets appear extracellularly. The fourth type is the atheromatous plaque, where lipids accumulate excessively and form lipid pools, and the intimal structure will be damaged. The fifth type is the fibrous atheromatous plaque, which is the most characteristic lesion of arterial atherosclerosis. The sixth type is a complex lesion, representing a severe condition.

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Cardiology
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What tests are used for arteriosclerosis?

If arteriosclerosis is in the early stages, we need to understand the situation with lipids and blood sugar, so lipid and blood glucose tests should be done. Later on, when some atheromatous plaques appear, examinations such as color Doppler ultrasound and cardiac echocardiography can be done to assess blood flow and the degree of narrowing in the vessels. For some severe narrowings, consider conducting a CTA, MRI, or angiography, which can non-invasively understand the lesions of arteriosclerosis. For some patients, if there is a need for interventional treatment, invasive, selective arterial angiography can be performed to understand the condition of the lesions. Therefore, different tests can be chosen at different stages.

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What medicine to take for arteriosclerosis?

Drug therapy is an important component of the treatment for atherosclerosis and mainly includes the following types. The first is to regulate blood sugar and lipids, keeping them under control to slow down the process of atherosclerosis. The second involves taking antiplatelet medications to prevent the formation of blood clots, especially since some plaques, particularly soft plaques, are prone to rupture. For some patients who have already formed blood clots, thrombolytic therapy might be considered, but this is not typically necessary for all patients. Additionally, because high blood pressure can accelerate the progression of atherosclerosis, some patients also need to take antihypertensive drugs. For patients with narrowed blood vessels and severe symptoms, such as angina, vasodilators, including nitrates, might be used. Therefore, the treatment choices may vary depending on the severity of the condition, and the modes of drug therapy differ. (Note: Specific medications should be taken under the guidance of a doctor.)