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Lung cancer
What is the treatment for lung cancer?
Treatment for lung cancer should be based on the pathological staging, the pathology type, the biological behavior of the lung cancer, and individualization, taking into account the patient's cardiopulmonary function and overall systemic condition to develop a personalized treatment plan. For non-small cell lung cancer and small cell lung cancer, the treatment approaches differ significantly. Therefore, it is advisable for patients to seek treatment at specialized hospitals, under the guidance of oncology specialists. Generally, treatment options for non-small cell lung cancer include surgical resection, adjunctive chemoradiation, neoadjuvant chemoradiation, targeted therapy, and immunotherapy. For small cell lung cancer, a comprehensive treatment plan combining chemoradiation, along with prophylactic cranial irradiation and other aggressive treatments, is recommended. Each individual's situation might differ, so it is important to focus on a personalized comprehensive treatment plan rather than a one-size-fits-all approach.
How is lung cancer treated?
For the treatment of lung cancer, it should currently be based on a comprehensive treatment method tailored to the patient's age, specific condition, nutritional status, economic condition, and the capabilities available at the hospital. It is particularly related to the stage of the disease and the type identified in the tissue biopsy. Currently, lung cancer primarily adopts a multidisciplinary comprehensive treatment approach spearheaded by surgical intervention. Surgical treatment is the preferred method for lung cancer, but since it is a systemic disease, surgery alone cannot completely address the issue. Therefore, it must be combined with radiotherapy, chemotherapy, and other treatments in a multidisciplinary and comprehensive approach. Additionally, immunotherapy and targeted therapy are inseparable and crucial parts of integrated treatment strategies for lung cancer. If the disease is staged and involves adenocarcinoma or squamous cell carcinoma of the lung, surgical treatment is recommended followed by adjuvant radiotherapy or chemotherapy, or targeted and immunotherapy. If surgery is not possible, some supportive treatments can be considered. For small-cell lung cancer, surgery is not recommended because it offers no benefit; instead, a combined approach of chemotherapy and radiotherapy is advised.
Staging of Lung Cancer
The staging of lung cancer is of great clinical significance for the selection of clinical treatment plans and the prediction of prognosis. According to the International Association for the Study of Lung Cancer and the World Health Organization, lung cancer is staged based on the size of the primary tumor (T stage), the condition of tumor lymph node metastasis (N stage), and the presence of distant metastases (M stage). Lung cancer is classified according to these criteria, which are used internationally. Currently, there are UICC staging and AJCC staging, which are two different systems.
How is lung cancer diagnosed?
Lung cancer is one of the malignant tumors and falls under respiratory system diseases. The gold standard for the diagnosis of malignant tumors is biopsy. Thus, lung cancer is no exception; it requires a biopsy and immunohistochemistry to determine the type of cancer and its pathological type. So how is the biopsy obtained? We can use a bronchoscope to directly observe the tumor and collect small tissue samples for pathological examination. Additionally, there is the thoracic wall lung puncture biopsy, where tissue from the tumor can be sampled using a fine needle. These samples are observed under a microscope to differentiate the pathological types and to further confirm the diagnosis.
Early symptoms of lung cancer
Early-stage lung cancer, especially peripheral lung cancer, often has no symptoms and is mostly found during chest X-rays or CT scans. The clinical symptoms of lung cancer are closely related to the location, size, pathological type of the tumor, whether it compresses or invades adjacent organs, and whether there is metastasis. The symptoms of lung cancer generally include: First, some symptoms of the primary tumor growing locally, including cough, hemoptysis, difficulty breathing, and chest pain. When the tumor grows inside a larger bronchus, it might cause some irritative coughing. Second, as the tumor continues to grow and affects the drainage of the bronchi, it may lead to secondary lung infections, presenting with symptoms such as cough and purulent sputum. Third, there might be bloody sputum streaked with blood or intermittent minor hemoptysis, though significant hemoptysis is very rare.
What causes lung cancer?
Lung cancer is caused by a variety of factors. Research indicates that lung cancer results from a combination of genetic defects, external and internal environmental factors, and personal factors. Numerous studies have confirmed that long-term and heavy smoking is the most significant carcinogenic factor for lung cancer. There is a positive correlation between the amount and duration of smoking and the incidence of lung cancer. The second factor is related to working in asbestos-related industries, which very much relates to the work environment, and also has a certain relation to smog. Indoor environmental pollution is also a very significant carcinogenic factor for lung cancer. This includes smoke from burning coal indoors, fumes from cooking oils in kitchens, and carcinogenic substances released by indoor decorating materials. Fourthly, internal human factors such as the immune status, metabolic abnormalities, genetic factors, and chronic lung infections are also related. The fifth factor involves irregular diet and rest habits, irritating foods, alcohol consumption, and heavy smoking.
What is good to eat for lung cancer?
For dietary recommendations regarding lung cancer, the first suggestion is to maintain a regular diet and lifestyle with a routine schedule, focusing on easy-to-digest and absorbable foods. The second suggestion is to enhance nutrition intake, for instance, by consuming more eggs, milk, and other high animal protein foods, such as quality protein sources. The third suggestion is to eat more healthy green foods, such as vegetables and fruits, focusing on fresh items. The fourth point is to advise against smoking and drinking alcohol, and to consume fewer irritating foods.
What are the symptoms of lung cancer?
The most common symptoms of lung cancer include coughing, particularly irritating coughs, and symptoms of coughing up blood. The blood in the sputum may appear as spots, streaks, or intermittent small amounts. Other symptoms include difficulty breathing and chest pain, as well as potential tightness in the chest, shortness of breath, and fever. Secondly, if lung cancer grows within the thoracic cavity and spreads, invading nearby tissues and organs, it can produce secondary symptoms. For example, paralysis of the phrenic nerve on the same side may lead to difficulty breathing and belching. Compression of the recurrent laryngeal nerve may cause hoarseness; compression of the superior vena cava can lead to distended veins in the face, neck, and upper limbs; subcutaneous edema; and if the pleura is invaded, it can cause pleural effusion, among other symptoms. If lung cancer metastasizes through the bloodstream, it may spread to the brain and potentially lead to symptoms such as headaches, nausea, and vomiting. Metastasis to different regions of the brain might cause various symptoms, including seizures, mental confusion, and vision impairment. In a minority of cases, lung cancer may produce endocrine substances, possibly leading to symptoms like severe muscle weakness, bone and joint pain, and other such symptoms.
Will people with lung cancer experience weight loss?
This question should be answered specifically. Some people may initially experience symptoms such as weight loss and fatigue when they start to develop lung cancer. Some people with better physical constitution may not lose weight so easily. However, if a malignant tumor persists in the body for a long time, it will consume the body's nutrients and lead to a state of cachexia, characterized by systemic toxicity symptoms including weight loss, fatigue, fever, and other similar symptoms.
Symptoms of brain metastasis from lung cancer
Brain metastasis of lung cancer is caused by hematogenous spread of lung cancer to the brain. Brain metastasis typically presents with symptoms such as headaches, nausea, and vomiting, including projectile vomiting. The headaches may be severe, and there may be abnormalities in sensory perception and motor function, possibly accompanied by seizures, mental confusion, olfactory disturbances, visual impairments, and other symptoms. The specific symptoms can vary depending on the location of the metastasis in the brain. However, most patients experience headaches, nausea, and vomiting. Individual differences are significant, and it's important to analyze the specific issues and the specific areas of the brain affected.