In clinical practice, the first choice of treatment for mild depression is generally psychotherapy, especially recommended cognitive behavioral therapy, psychodynamic therapy, and interpersonal therapy. In cognitive behavioral therapy, it is particularly important to help patients identify automatic thoughts, including teaching patients to recognize automatic thoughts, emotions, and behaviors. By correcting irrational cognitive patterns, such as catastrophizing, magnifying, and overgeneralization, a new cognitive system is reestablished to achieve effective treatment goals. Additionally, physical therapies like repetitive transcranial magnetic stimulation can also be chosen to alleviate symptoms of mild depression. However, for some patients with depression, pharmacotherapy can also be considered, particularly recommended are first-line serotonin reuptake inhibitors. It is crucial to follow the doctor's advice during the clinical treatment process and adhere to a systematic and standardized medication treatment throughout the illness.