The diagnosis of depression in clinical practice includes understanding the patient's clinical manifestations, conducting in-depth psychiatric examinations, scale measurements, and excluding auxiliary examinations related to depression. Clinically, it is important to fully understand the occurrence, development, progression, and treatment process of depression-related manifestations in patients. Additionally, psychiatric examinations focus on detailed assessments of the patients’ sensations, perceptions, consciousness, thinking, emotions, attention, memory, intelligence, and self-control, to further understand their overall psychological state. Scale measurements often involve self-assessment scales, depressive symptom self-rating scales or external assessment scales for comprehensive evaluation. Exclusion diagnostics primarily involve corresponding tests, such as thyroid examinations, to rule out physical diseases that may cause symptoms related to depression. After compiling all the information mentioned above, a definitive diagnosis of depression can be made.